Biomedical Engineering and Bioengineering Commons^™

Development Of A Bovine X Chromosome Linkage Group And Painting Probes To Assess Cattle, Sheep, And Goat X Chromosome Segment Homologies., Sakthikumar Ambady, F.Abel Ponce Leon, Gregory Hawkins, Steven Kappes, Michael Bishop, James Robl, Craig Beattle

Sakthikumar Ambady

The X chromosome linkage group is conserved in placental mammals. However, X chromosome morphological differences, due to internal chromosome rearrangements, exist among mammalian species. We have developed bovine chromosome painting probes for Xp and Xq to assess segment homologies between the submetacentric bovine X chromosome and the acrocentric sheep and goat X chromosomes. These painting probes and their corresponding DNA libraries were developed by chromosome micromanipulation, DNA micropurification, microcloning, and PCR amplification. The bovine Xp painting probe identified an interstitially located homologous segment in the sheep and goat Xq region, most probably resulting from chromosome inversion. Ten type II (microsatellite) …

Scanning Local‐Acceleration Microscopy, Nancy Burnham, A. Kulik, G. Gremaud, P. Gallo, F. Oulevey

Nancy A. Burnham

By adapting a scanning force microscope to operate at frequencies above the highest tip–sample resonance, the sensitivity of the microscope to materials’ properties is greatly enhanced. The cantilever’s behavior in response to high‐frequency excitation from a transducer underneath the sample is fundamentally different than to its low‐frequency response. In this article, the motivations, instrumentation, theory, and first results for this technique are described.

Materials’ Properties Measurements: Choosing The Optimal Scanning Probe Microscope Configuration, Nancy Burnham, G Gremaud, A Kulik, P Gallo, F Oulevey

Nancy A. Burnham

Rheological models are used to represent different scanning probe microscope configurations. The solutions for their static and dynamic behavior are found and used to analyze which scanning probe microscope configuration is best for a given application. We find that modulating the sample at high frequencies results in the best microscope behavior for measuring the stiffness of rigid materials, and that by modulating the tip at low frequencies and detecting the motion of the tip itself (not its position relative to the tip holder) should be best for studying compliant materials in liquids.

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Lai - Introduction To Continuum Mechanics ترجمه فارسي کتاب مکانيک محيط پيوسته ويرايش سوم, Dr Alireza Zolfaghari

Dr Alireza Zolfaghari

No abstract provided.