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A Magnetic Resonance Compatible Knee Extension Ergometer, Youssef Jaber Jan 2017

A Magnetic Resonance Compatible Knee Extension Ergometer, Youssef Jaber

Masters Theses

The product of this thesis aims to enable the study of the biochemical and physical dynamics of the lower limbs at high levels of muscle tension and fast contraction speeds. This is accomplished in part by a magnetic resonance (MR) compatible ergometer designed to apply a load as a torque of up to 420 Nm acting against knee extension at speeds as high as 4.7 rad/s. The system can also be adapted to apply the load as a force of up to 1200 N acting against full leg extension. The ergometer is designed to enable the use of ...


Changes In The Ultrastructural Features Of Estrogen Deficient Ovine Bone, Peter Mauer Jan 2014

Changes In The Ultrastructural Features Of Estrogen Deficient Ovine Bone, Peter Mauer

PhD theses

Osteoporosis is “a skeletal disorder characterised by compromised bone strength predis- posing to an increased risk of fracture” (NIH, 2001). Every second woman and every fifth man will suffer an osteoporotic fracture (Kanis et al., 2000). Of all people that suffer an age-related fracture, the current gold standard of osteoporosis diagnosis, DEXA scanning, misclassifies 80% of them to be non-osteoporotic (Sanders et al., 2006). Bone quantity is easily measured, however, bone strength is an interplay of bone quantity and quality — and the latter is hard to determine. More reliable clinical methods to diagnose osteoporosis are needed as well as widening ...