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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

Drug delivery

Theses

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Full-Text Articles in Biomedical Engineering and Bioengineering

Evaluation Of Methods To Account For Release From Nanofiber Scaffolds, Jennifer Moy May 2014

Evaluation Of Methods To Account For Release From Nanofiber Scaffolds, Jennifer Moy

Theses

Electrospinning is a common technique utilized to form fibers from the micro- to nanometer range. Nanofibers form through electrospinning can be utilized as scaffolds since the fiber structures are similar to the structures within the extracellular matrix. Researchers use additives, such as growth factors, to help facilitate cell proliferation and function. Also, researchers are attempting to use electrospun fibers for drug delivery and as wound dressings since the electrospun fibers have high surface area to volume ratio. In both situations, the release of either the additive or the drug needs to be controlled so that the fibers would release the ...