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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Role Of Nitric Oxide As A Modulator Of Platelet Dense Granule Release, Clifton Ford Frilot Ii
Role Of Nitric Oxide As A Modulator Of Platelet Dense Granule Release, Clifton Ford Frilot Ii
Doctoral Dissertations
Nitric oxide (NO) has been shown to suppress platelet activation, induce vasodilation, inhibit smooth muscle cell proliferation, and act against infection. Activated platelets generally have opposite effects from these. They secrete platelet-derived growth factor (PDGF), which stimulates smooth muscle growth, serotonin, which is a platelet agonist, and a number of agents that promote further platelet aggregation. However, activated platelets also produce NO through the enzymatic functions of the constitutive form of nitric oxide synthase (NOS). The primary functions of this capability are not yet completely understood. Due to its low molecular weight and high diffusivity, NO is quickly transported from …
Generation Of Oxygen Microbubbles In A Microchannel With Crosscurrent Liquid Flow, Sung Sam Kim
Generation Of Oxygen Microbubbles In A Microchannel With Crosscurrent Liquid Flow, Sung Sam Kim
Doctoral Dissertations
An alternative way of blood oxygenation is proposed by introducing small bubbles directly into the blood stream. To be used for blood oxygenation, the bubble should be small enough to pass through the capillary beds. To explore the feasibility of producing small bubbles, bubble formation phenomena in a crosscurrent liquid flow in a silicon microchannel were studied. Small orifices with 4 μm, 4.2 μm, and 6.6 μm hydraulic diameter were machined in a direction perpendicular to a trapezoidal channel that has a hydraulic diameter of 42 micrometers. These orifices were connected to three different chambers of 2.5 × 10−7 cm3, …
Evaluation Of 135- And 150-Degree Sliding Hip Screws, Kelly Blayne Crittenden
Evaluation Of 135- And 150-Degree Sliding Hip Screws, Kelly Blayne Crittenden
Doctoral Dissertations
Sliding hip screws are routinely used to repair Garden III femoral neck factures. This research seeks to better understand the influence of the hip screw angle on the performance of the fixation. The mechanics of fractured femurs repaired with 135- and 150-degree sliding fixation devices are explored using experimental, finite element, and analytical modeling. The experimental study involves testing of both intact and fixated femurs; the finite element work centers on two-dimensional models of intact and fixated femurs; and the analytical modeling explores the forces, moments and stresses in the fixation. The analytical model predicts that the screw will serve …