Open Access. Powered by Scholars. Published by Universities.®

Biomedical Engineering and Bioengineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Theses/Dissertations

2014

Electronic Theses and Dissertations

Daniel Felix Ritchie School of Engineering and Computer Science

Articles 1 - 2 of 2

Full-Text Articles in Biomedical Engineering and Bioengineering

Real-Time Bio Sensing Using Micro-Channel Encapsulated Mems Resonators, Ayesha Iqbal Aug 2014

Real-Time Bio Sensing Using Micro-Channel Encapsulated Mems Resonators, Ayesha Iqbal

Electronic Theses and Dissertations

This work presents a label-free bio-molecular detection technique based on realtime monitoring of the resonant frequency of micromechanical thermal-piezoresistive rotational mode disk resonators encapsulated in microfluidic channels. Mass loading via adsorption of molecular layers on the surface of such devices results in a frequency shift. In order to provide a reliable platform for sample-resonator interactions and to protect the resonators from contaminants, the resonators were encapsulated in PDMS-based microfluidic channels. Micro-channel encapsulation also allows insulation of electrical signals from the analyte solution. To characterize the performance of such devices as real-time label-free bio-molecular detectors, the strong non-covalent binding of Avidin ...


Design Of The High-Speed Stereo Radiography System, John C. Ivester Iv Aug 2014

Design Of The High-Speed Stereo Radiography System, John C. Ivester Iv

Electronic Theses and Dissertations

Orthopaedic pathologies often involve disruption of the mechanical environment of a joint at/below the mm scale. The ability to measure biomechanical kinematics at the sub-mm scale is essential for obtaining valuable insight into pathologies, but small motions of the joints are difficult to quantify. Estimates of skeletal kinematics are commonly made from optical motion capture systems and markers placed on the skin. The error caused by external marker movement is largely avoided with x-ray motion capture. Dynamic radiography uses a series of x-ray images recorded at high-speed and captures in-vivo joint motion. Uncovering the mechanical foundation of orthopaedic pathologies ...