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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

2014

Doctoral Dissertations

Cell motility

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Full-Text Articles in Biomedical Engineering and Bioengineering

Unlocking The Secrets Of Multi-Flagellated Propulsion, Stefan Oma Nwandu-Vincent Dec 2014

Unlocking The Secrets Of Multi-Flagellated Propulsion, Stefan Oma Nwandu-Vincent

Doctoral Dissertations

In this work, unique high-speed imaging platforms and an array of theoretical analysis methods are used to thoroughly investigate eukaryotic multi-flagellated propulsion using Tritrichomonas foetus as a test case. Through experimental observations through our imaging system with superior resolution and capture rate exceeding that of previous studies, it was discovered for the first time that the T. foetus employs a strategy similar to that of the “run and tumble” strategies found in bacteria and Chlamydomonas; it has two distinct flagellar beating patterns that result in two different body swimming motions, linear and turning swimming.

These two flagella patterns were ...