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Biomedical Engineering and Bioengineering Commons™
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- Biodectrics (1)
- Biodielectrics (1)
- Cerebral ischemia (1)
- DSI (1)
- DTI (1)
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- Deconvolution (1)
- Diffusion Phantom (1)
- Diffusion Spectrum Imaging (1)
- Diffusion weighted image (1)
- Electroporation (1)
- HARDI (1)
- High Angular Resolution Diffusion Imaging (1)
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- Nonosecond pulsed electric field (1)
- ODF (1)
- Orientation Distribution Function (1)
- Penumbra (1)
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Articles 1 - 5 of 5
Full-Text Articles in Biomedical Engineering and Bioengineering
Implementation Of Novel Group Delay Decomposition Method And Surgical Protocol For Assessing Peripheral Neuropathy, Sammy Paul Nicolas
Implementation Of Novel Group Delay Decomposition Method And Surgical Protocol For Assessing Peripheral Neuropathy, Sammy Paul Nicolas
Master's Theses
This paper outlines a surgical procedure for exposing and stimulating the sciatic nerve of an anesthetized rodent for purposes of obtaining conduction velocity readings. The ability to accurately quantify nerve conduction velocity has potential for use in the field of diagnostic medicine and disease characterization. An accurate reading depends on both the surgical method used to expose the desired nerve without imposing onto it any physical trauma as well as the stimulation protocol used to initiate action potentials. This paper contains the specific steps required to set up the necessary hardware and software for electrical stimulation as well as a …
Fmri Assessment Of Ischemic Stroke In Humans, Rui Yuan
Fmri Assessment Of Ischemic Stroke In Humans, Rui Yuan
Theses
Cerebral ischemia, or brain ischemia is a kind of stroke where the blood flow is insufficient to the metabolic demand of brain. The lack of oxygen supply will directly lead to the death of brain tissue. There are two major injury regions: the infarct and penumbra. Mostly, since the infarct regions became dead tissues rapidly after stroke, there is a tiny possibility to rescue them in time. But penumbra parts are different. Tissues there will be viable for hours after ischemia. Hence, both theoretically and practically, it is possible to salvage those cells in the penumbra region. Diffusion weighted image …
Novel Phantoms And Post-Processing For Diffusion Spectrum Imaging, Vaibhav Juneja
Novel Phantoms And Post-Processing For Diffusion Spectrum Imaging, Vaibhav Juneja
Dissertations & Theses (Open Access)
High Angular Resolution Diffusion Imaging (HARDI) techniques, including Diffusion Spectrum Imaging (DSI), have been proposed to resolve crossing and other complex fiber architecture in the human brain white matter. In these methods, directional information of diffusion is inferred from the peaks in the orientation distribution function (ODF). Extensive studies using histology on macaque brain, cat cerebellum, rat hippocampus and optic tracts, and bovine tongue are qualitatively in agreement with the DSI-derived ODFs and tractography. However, there are only two studies in the literature which validated the DSI results using physical phantoms and both these studies were not performed on a …
Testing The Efficiency Of Vertically Aligned Gold Nanowires On A Titanium Needle Implantable Neural Electrodes In The Rattus Norvegicus Hippocampus, Lauren Kegley
Electrical Engineering Undergraduate Honors Theses
Miniaturized multi-electrode arrays are MEMS devices that have found use as neural prosthetics (Neuro-MEMS). As implants they can interface with neurons as sensors or actuators and help compensate for loss of sensory input, motor control, or cognitive function. The micro-electrodes, studied here, were developed in-house. They have a vertically aligned gold nanowire array and are mounted on a sturdy fine gauge titanium needle. Hence, the bill of materials and design characteristics encourage its use as neural probe. For this study, a probe was tested in vivo for signal acquisition in the hippocampus of a Rattus Norvegicus (Sprague Dawley Rat). Using …
Nonosecond Pulsed Electric Field Induced Changes In Dielectric Properties Of Biological Cells, Jie Zhuang
Nonosecond Pulsed Electric Field Induced Changes In Dielectric Properties Of Biological Cells, Jie Zhuang
Electrical & Computer Engineering Theses & Dissertations
Nanosecond pulsed electric field induced biological effects have been a focus of research interests since the new millennium. Promising biomedical applications, e.g. tumor treatment and wound healing, are emerging based on this principle. Although the exact mechanisms behind the nanosecond pulse-cell interactions are not completely understood yet, it is generally believed that charging along the cell membranes (including intracellular membranes) and formation of membrane pores trigger subsequent biological responses, and the number and quality of pores are responsible for the cell fate. The immediate charging response of a biological cell to a nanosecond pulsed electric field exposure relies on the …