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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

2011

Traumatic brain injury

Articles 1 - 2 of 2

Full-Text Articles in Biomedical Engineering and Bioengineering

A Computational Investigation For Potential Improvements, Angela Grujicic Dec 2011

A Computational Investigation For Potential Improvements, Angela Grujicic

All Theses

Mild traumatic brain injury (mTBI), colloquially known as a concussion, is the most common injury in modern wars. This domination of mTBI is hypothesized to be due to a combination of unconventional explosives and better protection and care of the patients, increasing survivability. While the majority of the body is covered in armor, the head is left relatively unprotected. The current Advanced Combat Helmet (ACH) has been designed to protect the warfighter against ballistic impacts and impacts against a hard surface, with little to no regard to blast loading. Polyureas, a class of microsegregated, elastomeric copolymers, has been shown to …


Comparison Of Progression Of Diffuse Axonal Injury With Histology And Diffusion Tensor Imaging, Nisrine Zakaria Jan 2011

Comparison Of Progression Of Diffuse Axonal Injury With Histology And Diffusion Tensor Imaging, Nisrine Zakaria

Wayne State University Dissertations

Diffuse axonal injury, also known as traumatic axonal injury (TAI), is a major contributor to the pathology of traumatic brain injury. However, TAI is undetectable to conventional clinical magnetic resonance (MR) imaging techniques. Histologically, TAI is characterized by swollen axons that eventually disconnect and form axonal retraction balls (RB) in various white matter tracts. MR-diffusion tensor imaging (MR-DTI) has been reported to be sensitive to TAI in human TBI patients by measuring water molecular diffusion motion in white matter fiber tracts. To date, only one correlative animal study has been carried out to investigate the DTI relationship to TAI, and …