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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Anaerobic Fermentation Of Hemicellulose Present In Green Liquor And Hot Water Extracts To Carboxylic Acids, Rakhi Reddy Baddam May 2010

Anaerobic Fermentation Of Hemicellulose Present In Green Liquor And Hot Water Extracts To Carboxylic Acids, Rakhi Reddy Baddam

Electronic Theses and Dissertations

Wood is composed of cellulose, hemicellulose and lignin. In the paper industry the cellulose fraction is the major resource used in paper production, whereas the hemicellulose and the lignin are usually burned for heat recovery. Recently, wood-derived hemicellulose extracts have received much attention for the production of valuable bioproduct fuels and chemicals. Mixed-culture microbial ecosystems are capable of converting biomass materials, such as wood extracts, into mixtures of carboxylic acids (C1-C7), which can in turn be purified and sold as products, or converted into other organic chemicals through chemical means. The relative concentrations of the acids produced in the fermentations ...


Electrohydrodynamic Atomization For Improved Macromolecular Drug Delivery, Michelle Zeles-Hahn Jan 2010

Electrohydrodynamic Atomization For Improved Macromolecular Drug Delivery, Michelle Zeles-Hahn

Electronic Theses and Dissertations

With advances in drug research, the use of biological therapeutics is becoming a reality. Unfortunately, methods for processing and delivering these fragile macromolecules often limit their therapeutic potential. For this dissertation, we explore the aerosolization of macromolecules by way of electrohydrodynamic atomization (EHDA) and how this method can be used to process and deliver therapeutics. EHDA employs a high voltage to break a column of liquid into drops. It was unknown if or how the residual charge left of the resulting droplets would affect lung cells. An in vitro experiment was conducted to spray aerosolized DNA, by way of EHDA ...