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Full-Text Articles in Biomedical Engineering and Bioengineering

The Effect Of Cognitive Limb Embodiment On Vascular Physiological Response, Hala Elsir Mustafa Osman Jan 2018

The Effect Of Cognitive Limb Embodiment On Vascular Physiological Response, Hala Elsir Mustafa Osman

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The rubber hand illusion (RHI) is a visual-tactile perceptual illusion commonly used to study body ownership. In this paradigm, a rubber hand is positioned in front of a participant, and the person’s real hand is hidden from sight behind a barrier. When the real hand and the rubber hand are stroked synchronously, individuals perceive the rubber hand as if it were their own; it becomes “embodied.” This illusory experience of body ownership is associated with multimodal integration of touch and vision. From these visual-tactile-cognitive mechanisms, we establish that our hands belong to us when what we see matches what we …


Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag Jan 2018

Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag

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Kidney cyst expansion, stagnant fluid accumulation, and insufficient vascular supply can result in localized chronic ischemia-hypoxia in kidney cysts, as well as in normal renal epithelia adjacent to a cyst. We hypothesize that in normal epithelia near a cyst, the stabilization of Hypoxia Inducible Factor 1a (HIF1a), a major regulator of cellular response to hypoxia, can cause altered paracellular and transcellular transport, transforming a normal absorptive phenotype to a secretory and paracellularly leaky phenotype, leading to cyst expansion. Using 100 µmol/L cobalt chloride (CoCl2), HIF1a was stabilized in cellular nucleus of a mouse cortical collecting duct cell line (mCCD 1296 …