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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Effects Of Different Microenvironmental Conditions On The Growth And Differentiation Of Dental Pulp Stem Cells, Matthew Cupelli
Effects Of Different Microenvironmental Conditions On The Growth And Differentiation Of Dental Pulp Stem Cells, Matthew Cupelli
All Theses
Human teeth are very complex structures that are susceptible to many different pathologies due to poor dental health. Currently, there are many restorative methods to reestablish some of the function that teeth have, but the materials used in these methods all have drawbacks and cannot fully mimic the native teeth. Tissue engineering research groups have begun to explore regenerating bone or dental tissue using mesenchymal stem cells derived from the bone marrow. However, our group focuses on regenerating dental tissues using multipotent stem cells from dental pulp.
Dental pulp stem cells (DPSCs) have shown similarities to bone marrow stem cells …
Dynamic Endothelialization Of Aortic Heart Valve Scaffolds, Richard Pascal
Dynamic Endothelialization Of Aortic Heart Valve Scaffolds, Richard Pascal
All Theses
Cardiovascular disease is the number one killer worldwide affecting both the heart and blood vessels. Valvular heart disease can arise from calcification, and structural deterioration resulting in a stenotic or regurgitant valve incapable of proper function. With approximately 275,000 valve replacements performed annually worldwide, the need for replacement heart valves is well established. Currently, treatment of valvular heart disease is limited to two options (mechanical and bioprosthetic). Both replacement valves have their own drawbacks, which have driven research in the bioengineering field to focus on the development of a tissue engineered heart valve (TEHV) capable of growth and self-repair.
A …
An In Vitro Evaluation Of Dbm As A Tissue Engineered Scaffold, Stephanie Arnold
An In Vitro Evaluation Of Dbm As A Tissue Engineered Scaffold, Stephanie Arnold
All Theses
Over 500,000 bone graft procedures are performed each year in the United States. Bone grafting involves a surgical procedure to replace missing bone. Problems can arise with donor and defect sites during and after surgery, sometimes resulting in poor clinical results. The development and optimization of bone graft substitutes via a tissue engineering approach could markedly improve bone graft surgical outcome. Demineralized bone matrix (DBM), a bone graft material, is currently used in a clinical setting but has variable success rates.
The primary objective of the research presented in this thesis was to assess the cellular activity of D1 mouse …