Biomedical Engineering and Bioengineering Commons^™

Characterization And Performance Of Algal Biofilms For Wastewater Treatment And Industrial Applications, Maureen Kesaano

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study was carried out on algal biofilms grown using rotating algal biofilm reactors (RABRs) with the aim of: i) characterizing their growth in terms of photosynthetic activity and morphology ii) evaluating their performance as a wastewater treatment option and a feedstock for biofuels production, and iii) examining the algal-bacteria interactions.

A review of algal biofilm technologies currently employed in wastewater treatment processes was made to compare nutrient removal efficiencies, factors that influenced algal biofilm growth, and the different bioproducts generated from algal biomass. Consequently, research efforts were directed towards addressing pertinent issues identified in literature in order to optimize …

Anaerobic Co-Digestion Of Algal Biomass And A Supplemental Carbon Source Material To Produce Methane, Yousef Soboh

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The demand on alternative energy is rapidly increasing because the reserves of conventional fuel are decreasing and their impacts on the environment are increasing.
Developing renewable energy sources should receive utmost attention. The production of biofuels like methanol, biodiesel, and methane from various kinds of abundant biomass represents a very attractive energy source that can reduce the dependence on conventional fossil fuels energy.

Since algae contains high amounts of nitrogen and low carbon content, this research focused on anaerobic fermentation of algae to produce methane by blending algae with a supplemental carbon source material, sodium acetate. This was done to …

Microfabrication Of Bio-Analytical Devices: Microelectrode Array And Traveling-Wave Electrophoresis, Neil Draper

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The need for potable water is increasing with the ever-increasing world population. Further development of fast, portable, and cost effective analytical tools is necessary in order to create diagnostic techniques capable of supporting the water needs of the world’s population. Within the last decade microfluidics and Lab-on-a-Chip (LOC) technologies have increased the portability and speed of detection for aqueous samples. Photolithography techniques serve as a cost effective fabrication tool to create LOC electrodes on the micron scale.

An in-depth look at the fabrication process is undertaken in this paper in order to further the development of micro-scale detection techniques. An …

Microfabrication Of Electrochemical Analytical Devices For Detection Of Pathogen Species Dna And Toxic Metal Ions, Spencer Williams

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Water quality is a crucial factor in determining the health of an environment, and in turn the health of all those living in the given environment. Early detection of potential hazards in source water used for drinking would help to avoid outbreaks of sickness and even death. Contaminants, found in contact and drinking water, having negative effects on human health may include pathogenic microorganisms, and metal ion pollutants such as lead or cadmium. Lead and cadmium were selected due to well-known electrochemical properties providing easy references for developing new detection devices. Current methods for detection of these contaminants are extremely …

Bio-Inspired Materials And Micro/Nanostructures Enabled By Peptides And Proteins, Swathi Swaminathan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Bio-nanotechnology refers to the field of science that intersects nanotechnology with biology. The study involves in the creation of bio-mimetic devices that emulate elements and systems of nature finding use in various applications. Nanotechnology involves the characterization of nanomaterials along with the study of molecular self-assembly and nanoelectronics. Controlled binding and assembly of proteins onto nanomaterials is at the core of biological materials science and engineering with wide-ranging applications. This hybrid technology opens up several avenues in the field of sensors, pharmaceuticals, artificial implants and so on.

In this work, different biomaterials and polymers were characterized for phage displayed peptide …

Non-Catalytic Co-Gasification Of Sub-Bituminous Coal And Biomass, Guevara Che Nyendu

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Utilization of coal as a low-cost domestic energy source is becoming a subject of utmost importance due to fluctuating crude oil prices. However, coal use emits pollutants such as nitrous oxides (NO_x), sulfur oxides (SO_x), carbon dioxide (CO₂), and particulates that have negative environmental impact and significant issues on health. To minimize the harmful effects of coal use, renewable and sustainable biological or green materials called biomass are processed with coal to produce synthetic gas (syngas) that can be processed into clean energy fuels and value-added products.

Currently, coal is converted using combustion technology; …

Molecular Sensing And Imaging Of Human Disease Cells And Their Responses To Biochemical Stimuli, Lifu Xiao

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Advancement in microscopic and spectroscopic techniques could significantly improve our ability in the study and diagnosis of diseases. Especially, being able to image and detect human diseases at the cellular and molecular level allows people to diagnose diseases at early stages and to study the molecular mechanisms behind various diseases. Currently, histopathological techniques are most widely used for prognosis and diagnosis of human diseases. However, conventional histopathology requires a complex process of sample preparation, which limits the diagnostic efficiency of this technique. More importantly, it requires fixation of tissue or cell sample, making it unsuitable for the study of dynamic …

In Vitro, Non-Invasive Imaging And Detection Of Single Living Mammalian Cells Interacting With Bio-Nano-Interfaces, Qifei Li

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Study of bio-nano-interfaces of living mammalian cells will help the identification of cellular alterations (e.g. nucleic acids, amino acids, biomechanics, etc.) due to external stimuli, the design of biomaterials (e.g. nanoparticles, nanotubes) and the investigation on the interaction between cells and bio-nano-interfaces (e.g. cell differentiation on 3D nanostructured materials). The chemical, physical, and mechanical changes of mammalian cells interacting with biomaterials can be investigated by analytical techniques. In this dissertation, cellular responses and property changes are evaluated by non-invasive spectroscopic technique, Raman microscopy (RM), and atomic force microscopy (AFM) combined with traditional biological methods. This dissertation includes the biophysical, biochemical …

Catalytic Fast Pyrolysis Of Whole Field Pennycress Biomass, Yonas Afewerki Kidane

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

To satisfy the energy demand of the ever-increasing world population as well as to prevent environmental pollution arising from the use of fossil fuels, an alternate source of energy has to be developed. Biomass has the potential to provide a renewable energy source that is inexpensive and environmentally friendly. Field pennycress (Thlaspi arvense L.), previously considered as a weed, has now been found to be an ideal source of bio-fuel production. The focus of this research was to produce upgraded bio-oil by a process known as catalytic fast pyrolysis. A characterization and a temperature degradation profile study helped to …