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Full-Text Articles in Biomedical Engineering and Bioengineering

Influence Of Compressible Aerogel Electrodes On The Properties Of An Electrochemical Cell, Chris Sponheimer Jan 2010

Influence Of Compressible Aerogel Electrodes On The Properties Of An Electrochemical Cell, Chris Sponheimer

Electronic Theses and Dissertations

In the biomedical field the need for intra organ pressure measurement can only be facilitated by adapting existing pressure sensing technology to the specific tissues under test. The customization of these sensors has only driven up cost and the need to explore new technologies has become increasingly more important. For this dissertation, we explore the use of a new technology, particularly electrochemical pressure sensing to provide a low-cost pressure sensor to fill this need. Preliminary testing showed that electrically conductive polymers exhibited a change in voltage when pressurized if bubbles were first electrolyzed in the gel creating an aerogel, and …


Electrohydrodynamic Atomization For Improved Macromolecular Drug Delivery, Michelle Zeles-Hahn Jan 2010

Electrohydrodynamic Atomization For Improved Macromolecular Drug Delivery, Michelle Zeles-Hahn

Electronic Theses and Dissertations

With advances in drug research, the use of biological therapeutics is becoming a reality. Unfortunately, methods for processing and delivering these fragile macromolecules often limit their therapeutic potential. For this dissertation, we explore the aerosolization of macromolecules by way of electrohydrodynamic atomization (EHDA) and how this method can be used to process and deliver therapeutics. EHDA employs a high voltage to break a column of liquid into drops. It was unknown if or how the residual charge left of the resulting droplets would affect lung cells. An in vitro experiment was conducted to spray aerosolized DNA, by way of EHDA, …