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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Effects Of Micro-Features On Cell Detachment From Poly(N-Isopropylacrylamide) Coated Polydimethylsiloxane Membranes, Luke Webel
Williams Honors College, Honors Research Projects
The tested hypothesis was that features on polydimethylsiloxane (PDMS) surfaces coated with a poly(N-isopropylacrylamide)/aminopropyltriethoxysilane or pNIPAAM/APTES thin film would accelerate cell detachment than the film coated on a unfeatured surface. This project tested samples with features generated by molds, wrinkling, and sandpaper roughened substrates. Surface feature generation methods were limited to mechanical means, and characterized by microscopy and strain rates. 50/50 mixtures of 1.5 wt.% pNIPAAM/ APTES were used to coat thin films (30-40 nm) on PDMS membranes by spin-coating, and the coated membranes were thermally annealed to chemically graft pNIPAAm/APTES on the membrane and their thermo-responsive property was assessed …
Ergoscopetm – Ergonomic Endoscope, Drew Drum, John D'Egidio, Bethany Scarpitti, Ceara Stack, Sara Kerestman
Ergoscopetm – Ergonomic Endoscope, Drew Drum, John D'Egidio, Bethany Scarpitti, Ceara Stack, Sara Kerestman
Williams Honors College, Honors Research Projects
Medical endoscopy is a growing industry, with a trend of chronic hand pain for gastroenterologists and flexible endoscope users. In order to address the lack of ergonomics in traditional gastrointestinal (GI) flexible endoscopes, the design team collaborated with a GI professional to design a more ergonomic endoscope interface, focusing on the more problematic controls. Two prototypes, as well as a mock-up were fabricated, which underwent verification and a user evaluation to assess the design’s benefits. As the number of endoscopies each year increase, the Ergoscope, offers an alternative to the traditional angulation controls and muchneeded relief for the issues that …