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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

Missouri University of Science and Technology

Bioprinting

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Full-Text Articles in Biomedical Engineering and Bioengineering

3d Bioprinting A Pcl/13-93b3 Glass Composite And Its Potential Use As A Bio-Ink, Caroline Blair Murphy Jan 2017

3d Bioprinting A Pcl/13-93b3 Glass Composite And Its Potential Use As A Bio-Ink, Caroline Blair Murphy

Masters Theses

"A major limitation of using synthetic scaffolds in tissue engineering is little growth of incorporated cells in the interior of the scaffold, resulting in insufficient angiogenesis in the scaffold interior. Recently, cells have been 3D bioprinted concurrently with biomaterials to produce a cellularized, bioactive, angiogenic 3D environment. This thesis describes a novel solvent-extrusion method for printing polycaprolactone (PCL)/bioactive borate glass composite as a biomaterial for a cell-laden scaffold.

Bioactive borate glass was added to a mixture of PCL and organic solvent to make an extrudable paste, creating scaffolds measuring 10×10×1 mm3 in overall dimensions with pore ...