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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

California Polytechnic State University, San Luis Obispo

2016

COMSOL

Articles 1 - 2 of 2

Full-Text Articles in Biomedical Engineering and Bioengineering

Empirical Validation Of An In Silico Model Predicting The Fluid Dynamics Of An Iliac Artery Aneurysm, Rachel E. Willis Jun 2016

Empirical Validation Of An In Silico Model Predicting The Fluid Dynamics Of An Iliac Artery Aneurysm, Rachel E. Willis

Master's Theses

Iliac artery aneurysms are considered rare and difficult to detect and treat. Prompt diagnosis and timely intervention are essential, because the incidence of rupture is as high as 50%. The reported mortality rate for patients who undergo surgery for ruptured iliac artery aneurysm ranges from 50% to 70%. This study developed an in-vitro mechanical model of an iliac artery aneurysm to verify the accuracy of computer simulation software. Both the in vitro model and the in silico model can be used for further research to develop better treatment technology. This study also looks at the different types of iliac artery …


Fluid Flow Characterization In Rapid Prototyped Common Iliac Artery Aneurysm Molds, Daniel Cole Greinke Mar 2016

Fluid Flow Characterization In Rapid Prototyped Common Iliac Artery Aneurysm Molds, Daniel Cole Greinke

Master's Theses

The goal of this project was to determine whether i) fused deposition modeling could be employed to manufacture molds for vascular constructs, ii) whether vascular constructs could be created from these molds, and iii) to verify practical equivalence between observed fluid velocities. Dye tracking was to be employed to characterize fluid velocity profiles through the in vitro vascular constructs, including a half-vessel model and a full vessel model of an iliac artery aneurysm. A PDMS half-vessel construct was manufactured, and the movement of dye through the construct was tracked by a cellphone camera. Thresholds were applied to each video in …