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Biomedical Engineering and Bioengineering Commons™

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Theses/Dissertations

California Polytechnic State University, San Luis Obispo

Other Biomedical Engineering and Bioengineering

2018

Articles 1 - 4 of 4

Full-Text Articles in Biomedical Engineering and Bioengineering

Multi-Purpose Heart Valve Therapy Assembly Fixture, Alec John Foster, John Patrick Hofstetter, Emily Lim Jun 2018

Multi-Purpose Heart Valve Therapy Assembly Fixture, Alec John Foster, John Patrick Hofstetter, Emily Lim

Mechanical Engineering

STATEMENT OF CONFIDENTIALITY: The complete senior project report was submitted to the project advisor and sponsors. The results of this project are of a confidential nature and will not be published at this time.

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Preparation Of Supramolecular Amphiphilic Cyclodextrin Bilayer Vesicles For Pharmaceutical Applications, Kate E. Frischkorn Jun 2018

Preparation Of Supramolecular Amphiphilic Cyclodextrin Bilayer Vesicles For Pharmaceutical Applications, Kate E. Frischkorn

Master's Theses

Recent pharmaceutical developments have investigated using supramolecular nanoparticles in order to increase the bioavailability and solubility of drugs delivered in various methods. Modification of the carbohydrate cyclodextrin increases the ability to encapsulate hydrophobic pharmaceutical molecules by forming a carrier with a hydrophobic core and hydrophilic exterior. Guest molecules are commonly added to these inclusion complexes in order to add stability and further increase targeting abilities of the carriers. One such guest molecule is adamantine combined with a poly(ethylene glycol) chain. Vesicles are formed by hydrating a thin film of amphiphilic cyclodextrin and guest molecules in buffer solution that mimics physiological …

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Comparative Analysis Of Physiological Measurements And Environmental Metrics On Predicting Heat Stress Related Events, Mckenzie Lee Barlow Jun 2018

Comparative Analysis Of Physiological Measurements And Environmental Metrics On Predicting Heat Stress Related Events, Mckenzie Lee Barlow

Master's Theses

Exposure to high heat and humidity can lead to serious health risks, including heat exhaustion and heat stroke. Wet Bulb Globe Temperature (WBGT) and heat index have historically been used to predict heat stress events, but individualized factors are not included in the measurement. It has been shown that there is a relationship between cardiovascular measurements and heat stress, which could be used to measure heat stress risk on an individual level. Research has been done to find relationships between cardiovascular metrics in a workplace environment, however the study did not include the use of a controlled environment as a …

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Validation Of A 1d Algorithm That Measures Pulse Wave Velocity To Estimate Compliance In Blood Vessels, James Leung Jun 2018

Validation Of A 1d Algorithm That Measures Pulse Wave Velocity To Estimate Compliance In Blood Vessels, James Leung

Master's Theses

The purpose of this research is to determine if it is possible to validate the new 1D method for measuring pulse wave velocity in the aorta in vivo and estimate compliance. Arterial pressure and blood flow characterize the traveling of blood from the heart to the arterial system and have played a significant role in the evaluation of cardiovascular diseases. Blood vessel distensibility can give some information on the evolution of cardiovascular disease. A patient’s aorta cannot be explanted to measure compliance; therefore we are using a flow phantom model to validate the 1D pulse wave velocity technique to estimate …

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