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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones Nov 2022

Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones

Biomedical Engineering: Graduate Reports and Projects

This paper describes the design, manufacturing, and testing of a novel controllable hypoxic incubator with fully functional oxygen gas control and temperature control in a humid environment. On the current market, a majority of the few hypoxic incubators use pre-mixed gas that does not offer precise control over gas concentration. The objective for this project was to create a chamber that allows the user to set the O2 concentration to varying set points of % O2 while maintaining the chamber at a constant body temperature, CO2 level, humidity, and sterility. To start the project, multiple concepts were developed for the …


Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones Nov 2022

Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones

Master's Theses

This paper describes the design, manufacturing, and testing of a novel controllable hypoxic incubator with fully functional oxygen gas control and temperature control in a humid environment. On the current market, a majority of the few hypoxic incubators use pre-mixed gas that does not offer precise control over gas concentration. The objective for this project was to create a chamber that allows the user to set the O2 concentration to varying set points of % O2 while maintaining the chamber at a constant body temperature, CO2 level, humidity, and sterility. To start the project, multiple concepts were developed for the …


Eagle Medical Tray Denesting & Debris Removal Process, Nicholas Allen Ungefug, Noah Chavez, Susana Shu-Lin Okhuysen, Michael Augustine Pennington Jun 2022

Eagle Medical Tray Denesting & Debris Removal Process, Nicholas Allen Ungefug, Noah Chavez, Susana Shu-Lin Okhuysen, Michael Augustine Pennington

Industrial and Manufacturing Engineering

Eagle Medical Incorporated is a contract medical device packaging and sterilization company. The company purchases thermoformed medical packaging trays, which maintain the sterility of medical devices, from various manufacturers. To ensure packaging quality and to prevent cleanroom contamination, Eagle Medical inspects and sterilizes each blister tray that they order. This process is an essential non-value-added activity that creates a bottleneck. Cleanroom employees must stop packaging medical devices and attend to the processing of blister trays and packaging solutions. The blister trays arrive at Eagle’s facility in nested stacks. Vibration and movement during shipping further compresses the stacks, which makes separation …


Prosthetic Foot Shell, Ql+, Kathryn Victoria Versteeg, Jackson A. Tucker, Ethan William Frey Jun 2020

Prosthetic Foot Shell, Ql+, Kathryn Victoria Versteeg, Jackson A. Tucker, Ethan William Frey

Mechanical Engineering

This final design review includes an overview of our project and the steps we have taken to create our final product. We discuss the background research conducted, including various products like the foot shell we are trying to design and its related patents, along with similar past senior projects. As our product is considered a medical device, there are also certain standards that we must comply with. After determining our problem statement, we established what we believe to be the wants and needs of our user. These wants and needs were converted into specifications for our design, with durability as …


Tmtt Chimera Valve Attachment Process, Paulina Nguyen, Devin Debouk, Tamar Kazazian, Noah Thompson Jun 2020

Tmtt Chimera Valve Attachment Process, Paulina Nguyen, Devin Debouk, Tamar Kazazian, Noah Thompson

Biomedical Engineering

No abstract provided.


Sand Foot: A Prosthesis For Walking On Sand, Samantha A. Galicinao, John Dewing, Daniel Dugan Dotson, Christopher Urasaki Jun 2019

Sand Foot: A Prosthesis For Walking On Sand, Samantha A. Galicinao, John Dewing, Daniel Dugan Dotson, Christopher Urasaki

Biomedical Engineering

This critical design report describes the product development of a prosthesis for use on sand. Quality of Life Plus (QL+), a national non-profit organization aimed to develop prostheses for veterans and people with disabilities, introduced this project and its accompanying challenger, Sgt. Brady, to Cal Poly’s Interdisciplinary Senior Project class in September 2018. After consulting with Sgt. Brady and QL+ and performing extensive research, the Sand Foot team defined customer requirements and engineering specifications to meet these requirements. Comfortability, durability, and sandproof were key customer requirements. Several conceptual models were brainstormed and a final design was selected based on the …


Multi-Purpose Heart Valve Therapy Assembly Fixture, Alec John Foster, John Patrick Hofstetter, Emily Lim Jun 2018

Multi-Purpose Heart Valve Therapy Assembly Fixture, Alec John Foster, John Patrick Hofstetter, Emily Lim

Mechanical Engineering

STATEMENT OF CONFIDENTIALITY: The complete senior project report was submitted to the project advisor and sponsors. The results of this project are of a confidential nature and will not be published at this time.


Identification System For Heart Valve Manufacturing, Nicholas Robert Jensen, Edgar Davis Nix, Judith Evelyn Gonzalez, Albert Austin Liddicoat Jun 2018

Identification System For Heart Valve Manufacturing, Nicholas Robert Jensen, Edgar Davis Nix, Judith Evelyn Gonzalez, Albert Austin Liddicoat

Mechanical Engineering

Abstract withheld due to NDA constraints


Fixing Vertebral Compression Fractures With Medtronic, Kelly Fitzgerald, Trevor Bingham, Alex Denbaugh, Jordan Tang, Jon Stearns Jun 2018

Fixing Vertebral Compression Fractures With Medtronic, Kelly Fitzgerald, Trevor Bingham, Alex Denbaugh, Jordan Tang, Jon Stearns

Industrial and Manufacturing Engineering

No abstract provided.


Transcatheter Heart Valve Leaflet Assembly Tooling Improvement Final Design Report, James Craig Sherman, Zachary Robert Dicks, Luke Edward Williams Jun 2018

Transcatheter Heart Valve Leaflet Assembly Tooling Improvement Final Design Report, James Craig Sherman, Zachary Robert Dicks, Luke Edward Williams

Mechanical Engineering

Statement of Confidentiality: The complete senior project report was submitted to the project advisor and sponsor. The results of this project are of a confidential nature and will not be published at this time.


Annuloplasty Mti: Improved Tooling For Annuloplasty Ring Manufacturing, Justin David Smith, Spencer Lee Combs, Luke Edward Maly Jun 2018

Annuloplasty Mti: Improved Tooling For Annuloplasty Ring Manufacturing, Justin David Smith, Spencer Lee Combs, Luke Edward Maly

Mechanical Engineering

The complete senior project report was submitted to the project advisor and sponsor. The results of this project are of a confidential nature and will not be published at this time.


Dynamic Model For Simulating Motion Of The Right Ventricle, Brian Michael Larsen, Sam Koopman Porter, John Francis D'Ambrosio Jun 2018

Dynamic Model For Simulating Motion Of The Right Ventricle, Brian Michael Larsen, Sam Koopman Porter, John Francis D'Ambrosio

Mechanical Engineering

This report documents all the research, ideation, and mockups used to determine right ventricle motion and develop a system capable of reproducing that motion on a tissue sample. The model is intended for evaluating anchoring systems being developed by Edwards Lifesciences for use with tricuspid valve therapies. Several design solutions were considered for the primary functions of recreating motion of the right ventricle and attaching tissue to the device. From these ideas a primary means of producing motion and attaching tissue was selected. These ideas were then developed over the course of a school year to become the final system …


Usa Boccia Ball Ramp For Athletes With Quadriplegia, Alissa A. Koukourikos, Matthew Lee, Nathan Bernards Dec 2017

Usa Boccia Ball Ramp For Athletes With Quadriplegia, Alissa A. Koukourikos, Matthew Lee, Nathan Bernards

Mechanical Engineering

In this report, the design process in creating an assistive device for Boccia Classification 3 (BC3) players is outlined. The initial research steps, including research into the rules of the game, capabilities of the players, and existing products is documented to show where ideas for the product stemmed from. This transitions into requirements that the sponsor requested, and preliminary designs and ideas for the product. Finally, this report explains the details of the final design, which has been analyzed for safety, ease of use, and ability to function under different conditions. The processes of manufacturing and testing will also be …


Final Design Report: Polymer Fatigue Characterization Test Method, Wyatt Ayling, Tyler Price, Brandon Stell, Michela Upson Dec 2016

Final Design Report: Polymer Fatigue Characterization Test Method, Wyatt Ayling, Tyler Price, Brandon Stell, Michela Upson

Mechanical Engineering

Polylogix is a team dedicated to the design, build, and testing of a fatigue machine to simulate cyclic loading on a biomedical polymer. This project is sponsored by Endologix, Inc. to provide test data characterizing mechanical material properties of various formulations of polymer used in abdominal aortic aneurysm surgeries. With this project goal, the machine must be able to test the polymer at body conditions; these include a testing temperature of 37°C and a cycling frequency ranging from 1 Hz to 10 Hz. This report proposes the following solution to this design challenge: an AC motor-driven mechanism utilizing a planetary …


Transcatheter Heart Valve Subassembly Device, Adam Aslam, Matthew Bezkrovny, Daniel Degree Jun 2015

Transcatheter Heart Valve Subassembly Device, Adam Aslam, Matthew Bezkrovny, Daniel Degree

Mechanical Engineering

No abstract provided.


Sapien3 Comb Stitch Improvement For Edwards Lifesciences, William Harley, Thomas Pluschkell, John Mctigue, Garrett Reed Jun 2015

Sapien3 Comb Stitch Improvement For Edwards Lifesciences, William Harley, Thomas Pluschkell, John Mctigue, Garrett Reed

Mechanical Engineering

The complete senior project report was submitted to the project advisor and sponsor. The results of this project are of a confidential nature and will not be published at this time.


2d Wireform Process Improvement, Katy Conlin, Carlo Ebora, Jordan Gamble Jun 2014

2d Wireform Process Improvement, Katy Conlin, Carlo Ebora, Jordan Gamble

Mechanical Engineering

The body of this work has been created for Edwards Lifesciences in conjunction with senior project requirements. As such, the information produced and contained within is under a non‐disclosure agreement. As per request by sponsor, the body of the work will not be submitted to any outside parties, and the title page will serve as proof of completion.


Beach Wheelchair Project, Rory Aronson, Joshua Marcum, Samuel Coyne, Alex Hayes, Alexa Colburn, Max Hessel, Benedikt Strauss, Marvin Rimmele, Marco Pietsch Jun 2013

Beach Wheelchair Project, Rory Aronson, Joshua Marcum, Samuel Coyne, Alex Hayes, Alexa Colburn, Max Hessel, Benedikt Strauss, Marvin Rimmele, Marco Pietsch

Mechanical Engineering

The Beach Wheelchair, Sandcrawler, is a machine intended to help give people with disabilities the full beach experience. The non-profit organization Bridge II Sports sponsored this project, and tasked us with developing the design and fabricating a prototype. This chair has several features including a linkage mechanism that raises and lowers a chair relative to an external frame, hand crank drive with Gates Carbondrive belt and sprockets, buoyant Wheeleez balloon tires, and much more.


Edwards Lifesciences - Skirt To Frame Attachment Manufacturing Aid, Samuel Joda, Cesar Grimaldo, Patrick Hutchinson Jun 2013

Edwards Lifesciences - Skirt To Frame Attachment Manufacturing Aid, Samuel Joda, Cesar Grimaldo, Patrick Hutchinson

Mechanical Engineering

No abstract provided.


Guidance System, Kayaking For The Visually Impaired, D. Ryan Kirtland, Ryan Phife, William Gardner, Amy Johnson Jun 2013

Guidance System, Kayaking For The Visually Impaired, D. Ryan Kirtland, Ryan Phife, William Gardner, Amy Johnson

Biomedical Engineering

Quality Life Plus is working with Team River Runner to develop an assistive guidance system for veterans who want to remain active by kayaking, after sustaining an injury that impairs vision. This system allows these veterans to complete a slalom speed race independent of a personal guide in the water. The system incorporates 3 stations that each contain a speaker connected to a microcontroller system covered by a Pelican Case on a custom made buoy. During the slalom race, a kayaker will travel from shore towards buoy #1 as it omits sound from the speaker. As the kayaker moves around …


Handitrike - Recumbent Tricycle, Sean Higginson, Kevin Howie, Vinay Patel Dec 2012

Handitrike - Recumbent Tricycle, Sean Higginson, Kevin Howie, Vinay Patel

Mechanical Engineering

This report covers the design and construction of the recumbent racing tricycle for Mr. Robert T. Kelly, a disabled veteran. Unfortunately Rob’s right leg is five inches shorter than his left one and therefore is unable to properly operate standard cranks. Our team HandiTrike is composed of Sean Higginson, Kevin Howie, and Vinay Patel and our project requires us to come up with a design that is feasible to complete within the given three quarters, as well as allow Rob to gain full use of his tricycle. Currently Rob ‘s trike uses the standard crank set up found on most …