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Biomedical Engineering and Bioengineering Commons

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Theses/Dissertations

Molecular, Cellular, and Tissue Engineering

2010

Biomedical Engineering

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Full-Text Articles in Biomedical Engineering and Bioengineering

Characterization And Analysis Techniques Of A Dynamic In Vitro Blood-Brain Barrier Model, Ryan Everett Woodhouse Dec 2010

Characterization And Analysis Techniques Of A Dynamic In Vitro Blood-Brain Barrier Model, Ryan Everett Woodhouse

Biomedical Engineering

The blood-brain barrier (BBB) is responsible for maintaining the sensitive environment required by the brain. Although the BBB is necessary for proper functioning of the brain, it acts as an obstacle for doctors attempting to treat neurological disease. For a drug to act upon the brain, it must first pass through the discriminating BBB. For this reason, much research has been performed in recent years in order to create an in vitro model of the BBB on which drugs targeted for the central nervous system may be tested. The main goal of this project is to create an in vitro …