Biomedical Engineering and Bioengineering Commons^™

Experimental And Model-Based Terahertz Imaging And Spectroscopy For Mice, Human, And Phantom Breast Cancer Tissues, Tyler Bowman

Graduate Theses and Dissertations

The goal of this work is to investigate terahertz technology for assessing the surgical margins of breast tumors through electromagnetic modeling and terahertz experiments. The measurements were conducted using a pulsed terahertz system that provides time and frequency domain signals. Three types of breast tissues were investigated in this work. The first was formalin-fixed, paraffin-embedded tissues from human infiltrating ductal and lobular carcinomas. The second was human tumors excised within 24-hours of lumpectomy or mastectomy surgeries. The third was xenograft and transgenic mice breast cancer tumors grown in a controlled laboratory environment to achieve more data for statistical analysis.

Experimental …

Integration Of Instrumentation And Processing Software Of A Laser Speckle Contrast Imaging System, Jacob James Carrick

Dissertations, Master's Theses and Master's Reports - Open

Laser speckle contrast imaging (LSCI) has the potential to be a powerful tool in medicine, but more research in the field is required so it can be used properly. To help in the progression of Michigan Tech's research in the field, a graphical user interface (GUI) was designed in Matlab to control the instrumentation of the experiments as well as process the raw speckle images into contrast images while they are being acquired. The design of the system was successful and is currently being used by Michigan Tech's Biomedical Engineering department. This thesis describes the development of the LSCI GUI …

Coupling Of Audio Signals Into Afm Images, Matthew Manning

Honors Theses

It is well known that Atomic Force Microscopy imaging is capable of yielding high resolution results with of surfaces at the nanoscale. However, despite the device capabilities and vast applications, AFM microscopy is possibly the most prone to the creation of image artifacts. AFM imaging can easily, and is often, corrupted by various external forces. The most obvious and measurable form of external interference is of course the presence of ambient noise. Most AFM manufactures attempt to counter the effects of such noise on the imaging process through use of noise-proof or noise-resistant shields that cover the microscope aperture. Without …