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Weldon School of Biomedical Engineering Faculty Publications

1985

Articles 1 - 7 of 7

Full-Text Articles in Biomedical Engineering and Bioengineering

Writing A Scientific Paper Prior To The Research, Charles F. Babbs, Martha M. Tacker Jan 1985

Writing A Scientific Paper Prior To The Research, Charles F. Babbs, Martha M. Tacker

Weldon School of Biomedical Engineering Faculty Publications

The traditional approach to preparing a research report for publication is to begin writing after the study has been completed. We propose another approach- to write a "zeroth" draft before the study is begun. This approach helps to focus the investigator's attention during the planning stage on critical aspects of the study. The discipline of writing down the rationale, the methods, and the variety of possible outcomes and their significance helps to clarify the logic on which the study is based. If these are acceptable to all authors and colleagues in the zeroth draft, it is likely that the research …

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An Inspiration-Triggered Delivery System For Oxygen Therapy Via A Nasal Cannula, Philip Charles Krause, Charles F. Babbs Jan 1985

An Inspiration-Triggered Delivery System For Oxygen Therapy Via A Nasal Cannula, Philip Charles Krause, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Therapy for severe chronic lung disease currently includes the administration of supplemental oxygen to prevent breathlessness and tissue hypoxia. Although effective, this therapy is unnecessarily costly, because oxygen is administered to the patient during expiration as well as inspiration. To eliminate this inefficiency, a delivery system that senses the inspiratory effort and delivers oxygen to the patient only during inspiration was developed. The 11  5  8-cm flow control unit attaches easily to a portable oxygen supply. The components of the system have an expected life of five years, and the 9-Volt battery provides power for about one month …

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Endotracheal Versus Intravenous Epinephrine During Electromechanical Dissociation With Cpr In Dogs, Sandra H. Ralston, Willis A. Tacker, Lee Showen, Alice B. Carter, Charles F. Babbs Jan 1985

Endotracheal Versus Intravenous Epinephrine During Electromechanical Dissociation With Cpr In Dogs, Sandra H. Ralston, Willis A. Tacker, Lee Showen, Alice B. Carter, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

The dose-response curves of epinephrine given either IV or endotracheally (ET) were compared during resuscitation from electromechanical dissociation (EMD). Ten anesthetized dogs were subjected to a two-minute period of electrically induced ventricular fibrillation (VF) followed by defibrillation without CPR to produce EMD. Mechanical CPR was followed by injection of either ET or IV epinephrine. Successful response was defined as a return of pulsatile blood pressure within two minutes of drug administration. Using log-dose increments of epinephrine, experimental trials were repeated in each animal. The IV and ET median effective doses were 14 and 130 g/kg, respectively. When the trials were …

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Gastric Insufflation During Iac-Cpr And Standard Cpr In A Canine Model, Charles F. Babbs, William E. Schoenlein, Marc W. Lowe Jan 1985

Gastric Insufflation During Iac-Cpr And Standard Cpr In A Canine Model, Charles F. Babbs, William E. Schoenlein, Marc W. Lowe

Weldon School of Biomedical Engineering Faculty Publications

This study was undertaken to determine the effect of interposed abdominal compressions (IAC) during cardiopulmonary resuscitation (CPR) on gastric insufflation when the airway is not secured with an endotracheal tube. A canine model was used in which a common ventilation pressure was applied to separate cuffed esophageal and tracheal tubes. Gas entering the stomach was collected by a pre-placed gastrostomy tube leading to a bell spirometer. Gas entering the lungs was measured with a Wright Respirometer® in series with the endotracheal tube. During standard CPR, measurable gastric gas volume was collected in 28 of 30 trials (mean 215  93 …

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Joseph S. Redding's Contributions To Cardiac Resuscitation, Sandra H. Ralston, Charles F. Babbs Jan 1985

Joseph S. Redding's Contributions To Cardiac Resuscitation, Sandra H. Ralston, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

The experimental studies conducted by the late Joseph S. Redding over the past three decades with his students and colleagues form the scientific basis for many aspects of present cardiopulmonary resuscitation (CPR). Redding's research was characterized by its elegance, simplicity, common-sense reasoning, and clinical relevance. Much of his work conducted in the 1960's anticipated with uncanny accuracy some of the most actively discussed issues in resuscitation today (Table 1). Most interesting are Redding's classic studies related to diastolic arterial pressure and myocardial perfusion during CPR, abdominal binding, acid-base status, and use of methoxamine versus other adrenergic drugs for cardiac resuscitation. …

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Use Of Combined Systemic Hypothermia And Local Heat Treatment To Enhance Temperature Differences Between Tumor And Normal Tissues, Charles F. Babbs, William D. Voorhees Iii, Robert R. Clark, David P. Dewitt Jan 1985

Use Of Combined Systemic Hypothermia And Local Heat Treatment To Enhance Temperature Differences Between Tumor And Normal Tissues, Charles F. Babbs, William D. Voorhees Iii, Robert R. Clark, David P. Dewitt

Weldon School of Biomedical Engineering Faculty Publications

The feasibility of combining local heat treatment with wholebody hypothermia in an effort to improve therapeutic gain was assessed. Superficial, non perfused phantom tumors were fashioned in eight anesthetized mongrel dogs by transplantation of the spleen from the abdomen to a subcutaneous site on the hind limb. After pretreatment of the animal with the vasodilator hydralazine (0.5 mg/kg, IV) to enhance normal tissue perfusion, the spleen implant was heated with a 2450-MHz microwave diathermy apparatus, first with the animal's core body temperature in the normal range (39°C) and then after the animal had been packed in ice to reduce core …

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Electroventilation, L A. Geddes, William D. Voorhees, Charles F. Babbs, J A. Deford Jan 1985

Electroventilation, L A. Geddes, William D. Voorhees, Charles F. Babbs, J A. Deford

Weldon School of Biomedical Engineering Faculty Publications

Electroventilation is a term used to describe the production of inspiration by applying rhythmic bursts of short duration stimuli to extrathoracic electrodes to stimulate motor nerves to the inspiratory muscles. In the dog, the optimum site for the electrodes was found to be on the upper chest wall, bilaterally. The inspired volume increased with increasing current intensity. The maximum tidal volume attainable was about four times resting tidal volume. The ability of electroventilation to maintain arterial blood oxygen saturation without the production of cardiac arrhythmias was demonstrated in pentobarbital-anesthetized dogs. The technique has several potential applications and offers promise in …

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