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Full-Text Articles in Biomedical Engineering and Bioengineering
Anatomy, Implant Selection And Placement Influence Spine Mechanics Associated With Total Disc Replacement, Justin F.M. Hollenbeck
Anatomy, Implant Selection And Placement Influence Spine Mechanics Associated With Total Disc Replacement, Justin F.M. Hollenbeck
Electronic Theses and Dissertations
Through aging and injury, the intervertebral disc of the lumbar spine can undergo degeneration, leading to collapse of the vertebrae and low back pain, a symptom that affects half the adult population in any given year. In an effort to reduce low back pain, total disc replacement treatment removes the degenerated disc, restores natural height and lordosis of the segment, and preserves motion at the joint. Patient anatomy, implant selection, and implant placement play significant roles in a patient's outcomes after total disc replacement surgery. Thus, the objective of the work presented in this thesis was to develop a suite …
Representing Intersubject Variability With A Statistical Shape And Alignment Model Of The Knee, Chandreshwar Rao
Representing Intersubject Variability With A Statistical Shape And Alignment Model Of The Knee, Chandreshwar Rao
Electronic Theses and Dissertations
Prior statistical shape models have not considered multiple structures in the knee joint to characterize anatomic variation which are required to investigate joint mechanics further for the successful knee replacement. Accordingly, the study's objective was to develop statistical shape and alignment model (SSAM) to capture intersubject variability and demonstrate the ability to generate realistic instances for use in finite element analysis (FEA). SSAM described the variability in the training set of 20 subjects with a series of modes of variation obtained by performing principal component analysis (PCA). PCA produced modes of variation with the first 3 modes representing 70% and …