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Conference Papers

Computational fluid dynamics

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Full-Text Articles in Biomedical Engineering and Bioengineering

Development Of A Three Dimensional Prolapse Model To Simulate Physiological Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle Feb 2008

Development Of A Three Dimensional Prolapse Model To Simulate Physiological Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle

Conference Papers

Coronary stent implantation can improve blood flow in an artery that has been narrowed by the build up of arterial plaque. However, the haemodynamic effect of stent placement is unclear and may influence arterial restenosis (re-blockage). The degree of tissue prolapse between stent struts may be an important factor in predicting the restenosis rate of a stent due to the haemodynamic influence of the protruding tissue. In this paper a mathematical model has been developed to numerically predict the tissue prolapse for an artery implanted with a coronary stent. The prolapse model has been applied to the Gianturco-Roubin II (GR-II) …


Application Of Advanced Computational Modelling In The Comparison Of Stent Induced Coronary Flow Disturbances, Jonathan Murphy, Fergal Boyle Feb 2007

Application Of Advanced Computational Modelling In The Comparison Of Stent Induced Coronary Flow Disturbances, Jonathan Murphy, Fergal Boyle

Conference Papers

Coronary stent implantation can improve blood flow in an artery narrowed by the build up of arterial plaque. However, the haemodynamic effect of stent placement is unclear and may influence arterial restenosis (re-blockage). In this investigation computational fluid dynamics (CFD) was used to predict the non-Newtonian three-dimensional flow field in a coronary artery following implantation of two different stents. A graphical illustration of the stented areas affected to various degrees of wall shear stress (WSS) is presented for both the Palmaz-Schatz (PS) and the Gianturco-Roubin-II (GR-II) coronary stents. The axial WSS and wall shear stress gradient (WSSG) is also presented …


Evaluation Of Stent Design Based On The Haemodynamic Effect Of Coronary Stenting, Jonathan Murphy, Fergal Boyle Jan 2007

Evaluation Of Stent Design Based On The Haemodynamic Effect Of Coronary Stenting, Jonathan Murphy, Fergal Boyle

Conference Papers

No abstract provided.


Application Of Advanced Computational Modelling In The Numerical Prediction Of The Haemodynamic Impact Of Coronary Stent Implantation, Jonathan Murphy, Fergal Boyle Dec 2006

Application Of Advanced Computational Modelling In The Numerical Prediction Of The Haemodynamic Impact Of Coronary Stent Implantation, Jonathan Murphy, Fergal Boyle

Conference Papers

Coronary stent implantation can improve blood flow in an artery narrowed by the build up of arterial plaque. However, the haemodynamic effect of stent placement is unclear and may influence arterial restenosis (re-blockage). In this investigation the stent induced, non-Newtonian blood flow disturbances have been captured in a three dimensional computational domain. The results clearly show areas of low wall shear stress proximal and distal to the stent wires, a characteristic which is known to encourage restenosis. Furthermore, this computational method of observing the complex haemodynamics of the stent environment can be used in conjunction with medical trial data to …