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Full-Text Articles in Biomedical Engineering and Bioengineering

Validation Of Experimental And Finite Element Biomechanical Evaluation Of Human Cadaveric Mandibles, Shirish M. Ingawale, Deepak G. Krishnan, Tarun Goswami Jul 2022

Validation Of Experimental And Finite Element Biomechanical Evaluation Of Human Cadaveric Mandibles, Shirish M. Ingawale, Deepak G. Krishnan, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Background: Biomechanical analysis of human mandible is important not only to understand mechanical behavior and structural properties, but also to diagnose and develop treatment options for mandibular disorders. Therefore, the objective of this research was to generate analytical and experimental data on mandibles, construct custom 3D models, and compare the analytically derived maximum strains with strain gage data in five areas of interest for each mandible. Methods: We investigated the surface strains in the cadaveric human mandibles under different configurations of cyclic compressive loads in an experimental setting and compared these experimental strain data with results derived from computational finite …


Cyclic Damage Accumulation In The Femoral Constructs Made With Cephalomedullary Nails, Farah Hamandi, Alyssa Whitney, Mark H. Stouffer, Michael J. Prayson, Jorn Rittweger, Tarun Goswami Feb 2021

Cyclic Damage Accumulation In The Femoral Constructs Made With Cephalomedullary Nails, Farah Hamandi, Alyssa Whitney, Mark H. Stouffer, Michael J. Prayson, Jorn Rittweger, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Background: The purpose of this study was to evaluate the risk of peri-prosthetic fracture of constructs made with cephalomedullary (CM) long and short nails. The nails were made with titanium alloy (Ti-6Al-4V) and stainless steel (SS 316L). Methods: Biomechanical evaluation of CM nail constructs was carried out with regard to post-primary healing to determine the risk of peri-implant/peri-prosthetic fractures. Therefore, this research comprised of, non-fractured, twenty-eight pairs of cadaveric femora that were randomized and implanted with four types of fixation CM nails resulting in four groups. These constructs were cyclically tested in bi-axial mode for up to 30,000 cycles. All …


Alterations In Cardiac Motions Of The Failing Heart During Direct Mechanical Ventricular Actuation, Benjamin Allyn Schmitt Jan 2021

Alterations In Cardiac Motions Of The Failing Heart During Direct Mechanical Ventricular Actuation, Benjamin Allyn Schmitt

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Objectives: Heart failure (HF) refractory to medical management can be effectively treated with mechanical support. However, available devices are frequently associated with complications due to blood contact. Direct cardiac compression (DCC) devices augment LV systolic pump function by externally compressing the heart surface. Direct Mechanical Ventricular Actuation (DMVA) is a unique DCC method providing not only systolic but, importantly, diastolic support. However, DCC in general remains a relatively poorly understood modality. The purpose of this study was to examine DMVA’s effect on restoration of physiologic function in the failing heart. Methods: Global ischemic HF was induced with 5 mins of …


Optimization Of Wsu Total Ankle Replacement Systems, Bradley Jay Elliott Jan 2012

Optimization Of Wsu Total Ankle Replacement Systems, Bradley Jay Elliott

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Total ankle arthroplasty (TAR) is performed in order to reduce the pain and loss of ambulation in patients with various forms of arthritis and trauma. Although replacement devices fail by a number of mechanisms, wear in the polyethylene liner constitutes one of the dominating failure modes. This leads to instability and loosening of the implant. Mechanisms that contribute to wear in the liners are high contact and subsurface stresses that break down the material over time. Therefore, it is important to understand the gait that generates these stresses. Methods to characterize and decrease wear in Ohio TARs have been performed …


Cervical Spine Biomechanical Behavior And Injury, Mbulelo T. Makola Jan 2011

Cervical Spine Biomechanical Behavior And Injury, Mbulelo T. Makola

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A finite element model of the cervical spine including the C2 through C7 levels was developed in order to study the behavior of the cervical spine region. The model was validated in flexion extension, bending, and rotational load scenarios. The model was found to represent the biomechanical behavior of the cervical spine. The validated cervical spine finite element model was used to study spinal injury and disease processes. The model provided qualitative estimates of load carrying and stress distribution as well as range of motion.