Biomedical Engineering and Bioengineering Commons^™

Small Animal Thermal Support Device: Thermoregulation System For Scireq Flexivent Chamber, Alexander Dickey, Ashkhan Hojati, Matthew James, Kathleen Vermillera

Capstone Design Expo Posters

During ventilation induced lung injury (VILI) experiments, anesthetized mice lose the ability to regulate their core body temperature. Without maintaining homeostasis, the experimental data may be compromised due to changes in the rodent’s internal functions. Traditional heating techniques utilize a water circulation heating system that is unable to fit inside flexiVent ventilator testing chambers. The objective of this project is to design and build an automatic thermoregulatory feedback system to regulate the core body temperature of a mouse inside individual testing chambers throughout the duration of the experiment. The project deliverables include a functioning prototype that achieves safe and effective …