Biomedical Engineering and Bioengineering Commons^™

3d Micro-Ct For Functional Genomics, R. H. Johnson, Robert C. Molthen, Christopher C. Hanger, Kelly Lynn Karau, Steven Haworth, Christopher Dawson

Biomedical Engineering Faculty Research and Publications

No abstract provided.

Quantification Of Pulmonary Arterial Wall Distensibility Using Parameters Extracted From Volumetric Micro-Ct Images, Roger H. Johnson, Kelly Lynn Karau, Robert C. Molthen, Christopher A. Dawson

Biomedical Engineering Faculty Research and Publications

Stiffening, or loss of distensibility, of arterial vessel walls is among the manifestations of a number of vascular diseases including pulmonary arterial hypertension. We are attempting to quantify the mechanical properties of vessel walls of the pulmonary arterial tree using parameters derived from high-resolution volumetric x-ray CT images of rat lungs. The pulmonary arterial trees of the excised lungs are filled with a contrast agent. The lungs are imaged with arterial pressures spanning the physiological range. Vessel segment diameters are measured from the inlet to the periphery, and distensibilities calculated from diameters as a function of pressure. The method shows …

Anatomy Of Soft Tissues Of The Spinal Canal, Hogan Quinn, Jeffrey M. Toth

Biomedical Engineering Faculty Research and Publications

Background and Objectives.

Important issues regarding the spread of solutions in the epidural space and the anatomy of the site of action of spinal and epidural injections are unresolved. However, the detailed anatomy of the spinal canal has been incompletely determined. We therefore examined the microscopic anatomy of the spinal canal soft tissues, including relationships to the canal walls.

Methods.

Whole mounts were prepared of decalcified vertebral columns with undisturbed contents from three adult humans. Similar material was prepared from a macaque and baboon immediately on death to control for artifact of tissue change after death. Other tissues examined included …

The Use Of Recombinant Human Bone Morphogenetic Protein 2 (Rhbmp-2) To Promote Spinal Fusion In A Nonhuman Primate Anterior Interbody Fusion Model, Brian P. Hecht, Jeffrey S. Fischgrund, Harry N. Harkowitz, Lori Penman, Jeffrey M. Toth, Ali Shirkhoda

Biomedical Engineering Faculty Research and Publications

Study Design. A study on the efficacy of recombinant human bone morphogenetic protein 2 (rhBMP-2) in a nonhuman primate anterior interbody fusion model.

Objectives. To investigate the efficacy of rhBMP-2 with an absorbable collagen sponge carrier to promote spinal fusion in a nonhuman primate anterior interbody fusion model.

Summary of Background Data. RhBMP-2 is an osteoinductive growth factor capable of inducing new bone formation in vivo. Although dosage studies using rhBMP-2 have been performed on species of lower phylogenetic level, they cannot be extrapolated to the primate. Dosage studies on nonhuman primates are essential before proceeding with human primate application. …

Efficacy Of Beam-Hardening Correction For Vascular Morphometry Using 3d Conebeam Micro-Ct, Roger H. Johnson, Jiang Hsieh, Robert C. Molthen, Christopher A. Dawson

Biomedical Engineering Faculty Research and Publications

No abstract provided.

An Iterative Approach To The Beam Hardening Correction In Cone Beam Ct (Proceedings), Jiang Hsieh, Robert C. Molthen, Christopher A. Dawson, Roger H. Johnson

Biomedical Engineering Faculty Research and Publications

No abstract provided.