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Full-Text Articles in Biomedical Engineering and Bioengineering
Multimodal Sensory Integration For Perception And Action In High Functioning Children With Autism Spectrum Disorder, Nicole Marie Gregor Salowitz
Multimodal Sensory Integration For Perception And Action In High Functioning Children With Autism Spectrum Disorder, Nicole Marie Gregor Salowitz
Dissertations (1934 -)
Movement disorders are the earliest observed features of autism spectrum disorder (ASD) present in infancy. Yet we do not understand the neural basis for impaired goal-directed movements in this population. To reach for an object, it is necessary to perceive the state of the arm and the object using multiple sensory modalities (e.g. vision, proprioception), to integrate those sensations into a motor plan, to execute the plan, and to update the plan based on the sensory consequences of action. In this dissertation, I present three studies in which I recorded hand paths of children with ASD and typically developing (TD) …
Simultaneous Robotic Manipulation And Functional Magnetic Resonance Imaging: Feasibility In Children With Autism Spectrum Disorders, Nicole M.G. Salowitz, Bridget Dolan, Rheanna Remmel, Amy V. Van Hecke, Kristine M. Mosier, Lucia Simo, Robert A. Scheidt
Simultaneous Robotic Manipulation And Functional Magnetic Resonance Imaging: Feasibility In Children With Autism Spectrum Disorders, Nicole M.G. Salowitz, Bridget Dolan, Rheanna Remmel, Amy V. Van Hecke, Kristine M. Mosier, Lucia Simo, Robert A. Scheidt
Biomedical Engineering Faculty Research and Publications
An unanswered question concerning the neural basis of autism spectrum disorders (ASD) is how sensorimotor deficits in individuals with ASD are related to abnormalities of brain function. We previously described a robotic joystick and video game system that allows us to record functional magnetic resonance images (FMRI) while adult humans make goal-directed wrist motions. We anticipated several challenges in extending this approach to studying goal-directed behaviors in children with ASD and in typically developing (TYP) children. In particular we were concerned that children with autism may express increased levels of anxiety as compared to typically developing children due to the …