Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Biomedical optics (3)
- Cancer (2)
- Luminescence (2)
- Medicine (2)
- Tissue optics (2)
-
- Biological research (1)
- Biomedical engineering (1)
- Cameras (1)
- Cardiology (1)
- Clinical trials (1)
- Computer programming (1)
- Computing systems (1)
- Diagnostics (1)
- Flow cytometry (1)
- Fluorescence spectroscopy (1)
- Imaging systems (1)
- Infrared imaging (1)
- Infrared radiation (1)
- Medical research (1)
- Neuroscience (1)
- Optical components (1)
- Quality measurement (1)
- Receptors (1)
- Scientific research (1)
- Short wave infrared radiation (1)
- Spectroscopy (1)
- Statistical analysis (1)
- Surgery (1)
- Tissues (1)
- Translational research (1)
Articles 1 - 4 of 4
Full-Text Articles in Biomedical Engineering and Bioengineering
Biomedical Engineering Or Biomedical Optics: Will The Real Discipline Please Stand Up?, Brian W. Pogue
Biomedical Engineering Or Biomedical Optics: Will The Real Discipline Please Stand Up?, Brian W. Pogue
Dartmouth Scholarship
This editorial reflects on the shape of biomedical engineering as a discipline, and its relation to biomedical optics.
Characterizing Short-Wave Infrared Fluorescence Of Conventional Near-Infrared Fluorophores, Brook K. Byrd, Margaret R. Folaron, Joseph P. Leonor, Rendall R. Strawbridge, Xu Cao, Petr Bruza, Scott C. Davis
Characterizing Short-Wave Infrared Fluorescence Of Conventional Near-Infrared Fluorophores, Brook K. Byrd, Margaret R. Folaron, Joseph P. Leonor, Rendall R. Strawbridge, Xu Cao, Petr Bruza, Scott C. Davis
Dartmouth Scholarship
The observed behavior of short-wave infrared (SWIR) light in tissue, characterized by relatively low scatter and subdiffuse photon transport, has generated considerable interest for the potential of SWIR imaging to produce high-resolution, subsurface images of fluorescence activity in vivo. These properties have important implications for fluorescence-guided surgery and preclinical biomedical research. Until recently, translational efforts have been impeded by the conventional understanding that fluorescence molecular imaging in the SWIR regime requires custom molecular probes that do not yet have proven safety profiles in humans. However, recent studies have shown that two readily available near-infrared (NIR-I) fluorophores produce measurable SWIR fluorescence, …
Diagnostic Performance Of Receptor-Specific Surgical Specimen Staining Correlates With Receptor Expression Level, Jasmin M. Schaefer, Connor W. Barth, Scott C. Davis, Summer L. Gibbs
Diagnostic Performance Of Receptor-Specific Surgical Specimen Staining Correlates With Receptor Expression Level, Jasmin M. Schaefer, Connor W. Barth, Scott C. Davis, Summer L. Gibbs
Dartmouth Scholarship
Intraoperative margin assessment is imperative to cancer cure but is a continued challenge to successful surgery. Breast conserving surgery is a relevant example, where a cosmetically improved outcome is gained over mastectomy, but re-excision is required in >25 % of cases due to positive or closely involved margins. Clinical translation of margin assessment modalities that must directly contact the patient or required administered contrast agents are time consuming and costly to move from bench to bedside. Tumor resections provide a unique surgical opportunity to deploy margin assessment technologies including contrast agents on the resected tissues, substantially shortening the path to …
Ensuring Scientific Publishing Credibility In Translational Biomedical Optics., Brian W. Pogue
Ensuring Scientific Publishing Credibility In Translational Biomedical Optics., Brian W. Pogue
Dartmouth Scholarship
Optics has consistently been the largest singular technology sector used in medicine, and major advances in biomedical optics are documented daily in peer-reviewed publications. However, the academic stature of this field can be damaged by weaknesses in scientific publishing, where a “credibility crisis” has emerged as a popularized and increasingly studied dialogue. While there are still relatively few overt cases of fraud or erroneous research, more insidious aspects are seen in papers with results that have either low statistical power, selective reporting of observations, or data or computer codes that cannot be independently verified. Interestingly, the same solutions that improve …