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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Ultrahigh Field Magnetic Resonance Imaging – Technical Development And Translational Applications, Judy Alper
Ultrahigh Field Magnetic Resonance Imaging – Technical Development And Translational Applications, Judy Alper
Dissertations and Theses
Magnetic resonance imaging (MRI) may be used to provide detailed images of the human body with excellent soft tissue contrast. Alongside its current widespread clinical applications for diagnosis and treatment, MRI allows researchers to measure structure and function of different tissue types in order to advance our understanding of human biology and enable new medical applications of MRI. In particular, diseases affecting nerves and vessels, such as trigeminal neuralgia, with uncertain etiology can be studied using multiple MRI modalities so that treatment planning can we more effective and patient outcomes can be improved. Ultrahigh field MRI scanners, such as those …
Direct Current Stimulation Modulates Ltp And Ltd: Activity-Dependence And Dendritic Effects, Gregory Kronberg
Direct Current Stimulation Modulates Ltp And Ltd: Activity-Dependence And Dendritic Effects, Gregory Kronberg
Dissertations and Theses
Transcranial direct current stimulation (tDCS) has been reported to improve various forms of learning in humans. Stimulation is often applied during training, producing lasting enhancements that are specific to the learned task. These learning effects are thought be mediated by altered synaptic plasticity. However, the effects of DCS during the induction of endogenous synaptic plasticity remain largely unexplored. To model endogenous plasticity I induced long-term potentiation (LTP) and depression (LTD) at Schaffer collateral synapses in CA1 of rat hippocampal slices. When induction was paired with concurrent DCS, the resulting plasticity was biased towards potentiation, such that LTP was enhanced and …