Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
- Bioimaging and Biomedical Optics (1)
- Biomaterials (1)
- Biomedical Devices and Instrumentation (1)
- Medical Specialties (1)
-
- Medicine and Health Sciences (1)
- Molecular, Cellular, and Tissue Engineering (1)
- Movement and Mind-Body Therapies (1)
- Nanoscience and Nanotechnology (1)
- Neurology (1)
- Osteopathic Medicine and Osteopathy (1)
- Psychiatry (1)
- Psychiatry and Psychology (1)
- Radiology (1)
- Rehabilitation and Therapy (1)
- Surgical Procedures, Operative (1)
Articles 1 - 2 of 2
Full-Text Articles in Biomedical Engineering and Bioengineering
Carboxymethylcellulose Hydrogels Support Central Nervous System-Derived Tumor-Cell Chemotactic Migration: Comparison With Conventional Extracellular Matrix Macromolecules, Tanya Singh, Chandrasekhar Kothapalli, Devika Varma, Steven B. Nicoll, Maribel Vazquez
Carboxymethylcellulose Hydrogels Support Central Nervous System-Derived Tumor-Cell Chemotactic Migration: Comparison With Conventional Extracellular Matrix Macromolecules, Tanya Singh, Chandrasekhar Kothapalli, Devika Varma, Steven B. Nicoll, Maribel Vazquez
Publications and Research
The local microenvironment plays an important role in maintaining the dynamics of the extracellular matrix and the cell-extracellular matrix relationship. The extracellular matrix is a complex network of macromolecules with distinct mechanical and biochemical characteristics. Disruptions in extracellular matrix homeostasis are associated with the onset of cancer. The extracellular matrix becomes highly disorganized, and the cell-matrix relationship changes, resulting in altered cell-signaling processes and metastasis. Medulloblastoma is one of the most common malignant pediatric brain tumors in the United States. In order to gain a better understanding of the interplay between cell-extracellular matrix interactions and cell-migratory responses in tumors, eight …
Utilizing Fast Spin Echo Mri To Reduce Image Artifacts And Improve Implant/Tissue Interface Detection In Refractory Parkinson’S Patients With Deep Brain Stimulators, Subhendra N. Sarkar, Pooja R. Sarkar, Efstathios Papavassiliou, Rafael Rojas
Utilizing Fast Spin Echo Mri To Reduce Image Artifacts And Improve Implant/Tissue Interface Detection In Refractory Parkinson’S Patients With Deep Brain Stimulators, Subhendra N. Sarkar, Pooja R. Sarkar, Efstathios Papavassiliou, Rafael Rojas
Publications and Research
Introduction. In medically refractory Parkinson’s disease (PD) deep-brain stimulation (DBS) is an effective therapeutic tool. Postimplantation MRI is important in assessing tissue damage and DBS lead placement accuracy. We wanted to identify which MRI sequence can detectDBS leads with smallest artifactual signal void, allowing better tissue/electrode edge conspicuity.
Methods. Using an IRB approved protocol 8 advanced PDpatientswere imagedwithinMRconditional safety guidelines at lowRF power (SAR ≤ 0.1 W/kg) in coronal plane at 1.5T by various sequences.The image slices were subjectively evaluated for diagnostic quality and the lead contact diameters were compared to identify a sequence least affected by metallic leads.
Results …