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Biomedical Engineering and Bioengineering Commons

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Physical Sciences and Mathematics

MRNA

2012

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Full-Text Articles in Biomedical Engineering and Bioengineering

Correct Spectral Conversion Between Surface‐Enhanced Raman And Plasmon Resonance Scattering From Nanoparticle Dimers For Single‐Molecule Detection, Kyuwan Lee Dec 2012

Correct Spectral Conversion Between Surface‐Enhanced Raman And Plasmon Resonance Scattering From Nanoparticle Dimers For Single‐Molecule Detection, Kyuwan Lee

Kyuwan Lee

Simultaneous measurement of surface-enhanced Raman scattering (SERS) and localized surface plasmon resonance (LSPR) in nanoparticle dimers presents outstanding opportunities in molecular identification and in the elucidation of physical properties, such as the size, distance, and deformation of target species. SERS–LSPR instrumentation exists and has been used under limited conditions, but the extraction of SERS and LSPR readouts from a single measurement is still a challenge. Herein, the extraction of LSPR spectra from SERS signals is reported and a tool for measuring the interparticle distance from Raman enhancement data by the standardization of the SERS signal is proposed. The SERS ...