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Full-Text Articles in Biomedical Engineering and Bioengineering

Seeing Eye To Eye: A Machine Learning Approach To Automated Saccade Analysis, Maigh Attre May 2019

Seeing Eye To Eye: A Machine Learning Approach To Automated Saccade Analysis, Maigh Attre

Honors Scholar Theses

Abnormal ocular motility is a common manifestation of many underlying pathologies particularly those that are neurological. Dynamics of saccades, when the eye rapidly changes its point of fixation, have been characterized for many neurological disorders including concussions, traumatic brain injuries (TBI), and Parkinson’s disease. However, widespread saccade analysis for diagnostic and research purposes requires the recognition of certain eye movement parameters. Key information such as velocity and duration must be determined from data based on a wide set of patients’ characteristics that may range in eye shapes and iris, hair and skin pigmentation [36]. Previous work on saccade analysis ...


Algorithms For Enhancing Pattern Separability, Feature Selection And Incremental Learning With Applications To Gas Sensing Electronic Nose Systems , Robi Polikar Jan 2000

Algorithms For Enhancing Pattern Separability, Feature Selection And Incremental Learning With Applications To Gas Sensing Electronic Nose Systems , Robi Polikar

Retrospective Theses and Dissertations

Three major issues in pattern recognition and data analysis have been addressed in this study and applied to the problem of identification of volatile organic compounds (VOC) for gas sensing applications. Various approaches have been proposed and discussed. These approaches are not only applicable to the VOC identification, but also to a variety of pattern recognition and data analysis problems. In particular, (1) enhancing pattern separability for challenging classification problems, (2) optimum feature selection problem, and (3) incremental learning for neural networks have been investigated;Three different approaches are proposed for enhancing pattern separability for classification of closely spaced, or ...


Medical Image Tomography: A Statistically Tailored Neural Network Approach , John Patrick Kerr Jan 1994

Medical Image Tomography: A Statistically Tailored Neural Network Approach , John Patrick Kerr

Retrospective Theses and Dissertations

In medical computed tomography (CT) the tomographic images are reconstructed from planar information collected 180∘ to 360∘ around the patient. In clinical applications, the reconstructions are typically produced using a filtered backprojection algorithm. Filtered backprojection methods have limitations that create a high percentage of statistical uncertainty in the reconstructed images. Many techniques have been developed which produce better reconstructions, but they tend to be computationally expensive, and thus, impractical for clinical use;Artificial neural networks (ANN) have been shown to be adept at learning and then simulating complex functional relationships. For medical tomography, a neural network can be trained to ...


Miniaturized Chemical Sensors For Physiological Monitoring In Space Exploration , Shelley Jean Coldiron Jan 1993

Miniaturized Chemical Sensors For Physiological Monitoring In Space Exploration , Shelley Jean Coldiron

Retrospective Theses and Dissertations

This thesis describes the development of a dual-beam, fiber optic instrument for solution-phase analysis of thin-film sensors. Colorimetric indicators are described for incorporation into porous polymeric films. The films are immobilized at the distal ends of optical fibers and yield an optical response proportional to the target analyte. In its present form, the instrument functions in an absorbance mode as a solid-state, dual-wavelength photometer and is equipped with a custom-designed microprocessor controller and data processor. The described study encompasses interdisciplinary research in the fields of biomedical engineering, synthetic organic chemistry, interfacial chemistry, materials science, and computer and electrical engineering;The ...


Effects Of Randomly Rough Surfaces On Ultrasonic Inspection , Mehmet Bilgen Jan 1993

Effects Of Randomly Rough Surfaces On Ultrasonic Inspection , Mehmet Bilgen

Retrospective Theses and Dissertations

Surface finish of an industrial part affects its ultrasonic inspection and consequently the surfaces are often machined smooth before the evaluation. Ultrasonic inspection through smooth surfaces has been well studied and understood. A theoretical basis has been established for the characterization of interior cracks, voids and inclusions, and vast amount of literature exists. However, much less is known about quantitative ultrasonic inspection of such flaws in parts with rough surfaces, e.g. machine marks or "as-cast" surfaces. A question arises "When can an industrial part with randomly rough surfaces be inspected robustly using ultrasound?" This dissertation is aimed at answering ...


Development Of An Ocular Drug Release System For Cattle , Thomas Quang Dinh Jan 1991

Development Of An Ocular Drug Release System For Cattle , Thomas Quang Dinh

Retrospective Theses and Dissertations

An erodible ring-shaped ocular insert containing an antibiotic (tylosin tartrate) has been developed for treatment of infectious bovine keratoconjunctivitis (IBK). Four additional tasks have been completed: (1) a test to determine the retention time of the ocular device in the eyes of the calves, (2) an in vitro test to determine the degradation characteristics of the device, (3) an in vitro study to obtain the drug release profiles of the insert, and (4) a study to compare the use of rings and a field treatment method using infected cattle;The device remained in the eyes an average of 3.92 ...