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Biomedical Engineering and Bioengineering Commons™
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Articles 1 - 5 of 5
Full-Text Articles in Biomedical Engineering and Bioengineering
Investigating The Shelf Life Of Benzoyl Peroxide Coated Nozzles For Bone Cement Application, Alysen Leigh Demzik
Investigating The Shelf Life Of Benzoyl Peroxide Coated Nozzles For Bone Cement Application, Alysen Leigh Demzik
Honors Capstone Projects - All
Two-solution bone cements (TSBC) were developed to address the limitations of current powder-liquid bone cements, however are characterized by a limited shelf life due to spontaneous free radical polymerization. As a solution to pre-polymerization concerns, the initiator benzoyl peroxide (BPO) was removed from the cement solution and incorporated into a thin film coating within the static mixing nozzle, allowing the BPO to integrate with the TSBC as it is mixed for use. Only short-term storage of BPO-coated nozzles and the subsequent effects on bone cement properties is known. The goal of this study was to investigate the effects of time, …
A Study Of Ciliary Beating In Chlamydomonas, Xin Li
A Study Of Ciliary Beating In Chlamydomonas, Xin Li
Honors Capstone Projects - All
The goal of this research is to understand how a unicellular green alga, Chlamydomonas-reinhardtii, responds to red light (670nm) and sound waves, by monitoring the beating frequency of its two cilia, which control cell motility. Ciliary beating frequency (BF) is proportional to the production of ATP, mainly generated by photosynthesis. A photosynthesis inhibitor, 3-(3-, 4-dichlorophenyl)-1, 1-dimethylurea (DCMU) decreases ATP production by photosynthesis. I used DCMU as a tool to analyze the red light effect on BF.
In the process of studying the effect of red light, I unexpectedly discovered experimental conditions for unstable ciliary beating (as shown in the video). …
The Effect Of Maternal Diet On Fetal Development, Catherine Wilcox
The Effect Of Maternal Diet On Fetal Development, Catherine Wilcox
Honors Capstone Projects - All
Using mice as a model system, this study aimed to compare the effect of a high fat diet (HFD), high sugar diet (HSD) and a control diet (CD) on fetal growth and development at the time of birth (post-natal day 0 or PND 0), post-natal day 7 (PND 7) and post-natal day 14 (PND 14). Published literature has documented the effects of a negative in-utero environment on fetal development, but currently there is limited research regarding the continued effects on development after birth. Mouse pups were harvested and then imaged in 3-D using a high-resolution micro-computed tomography (micro-CT) system. Total …
Waste To Work Using Eccrine Sweat Battery Modules To Enhance Pedestrian Safety, Lauren J. Vesty
Waste To Work Using Eccrine Sweat Battery Modules To Enhance Pedestrian Safety, Lauren J. Vesty
Honors Capstone Projects - All
There is a need for increased pedestrian visibility. Improved athletic clothing with built in visibility features would enhance a roadside athlete’s safety. This experiment aims to create such an athletic shirt, while incorporating wearable biotechnology. A sweat battery that produced a voltage of 0.49 V and a current of 5.16 mA was created to power the visibility aspects of the shirt. The battery uses an aluminum anode, a carbon cathode, a sponge block as the container and semi-permeable membrane, and the body’s eccrine sweat as the electrolyte solution. The battery cells were arranged into blocks to produce an optimal current …
Loss Of Visual Function In Light-Stressed Mice, Ana Stachowiak
Loss Of Visual Function In Light-Stressed Mice, Ana Stachowiak
Honors Capstone Projects - All
Because of the highly devastating effects of retinal degenerative diseases, the study of mechanisms of vision loss is imperative. Age-related macular degeneration (AMD) is the leading causes of blindness in the elderly. In this study I examined how extreme light exposure, which causes light stress in rodents, affects the visual and retinal function of 3 strains of mice. I hypothesized that, three strains of mice, C57BL/6J, ALR/Lj and BALB/c, would all show significant changes in visual and retinal function. I used behavior testing to assess visual acuity and contrast sensitivity as well as electroretinogram (ERG) recordings to assess retinal function. …