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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Peptoid-Functionalized Gold Nanoparticles For Zika Virus Envelope Protein Detection, Meagan Olsen
Peptoid-Functionalized Gold Nanoparticles For Zika Virus Envelope Protein Detection, Meagan Olsen
Chemical Engineering Undergraduate Honors Theses
Detection and identification of viral pathogens is essential in providing effective and rapid medical treatment. Well-established detection methods can be expensive, slow, and sometimes unable to provide the needed sensitivity and specificity. The Zika virus is one clinically relevant pathogen that cannot be easily identified due to cross-reactivity with other viruses from the same family. Electrochemical sensors enhanced with peptoid-functionalized gold nanoparticles (AuNPs) are an alternative to traditional techniques that offers rapid, accurate, label-free pathogen detection for point-of-care diagnostics. To this end, a peptoid capable of binding to the Zika virus envelope protein was developed and its binding affinity for …
Fabrication Of Flexible, Biofunctional Architectures From Silk Proteins, Ramendra K. Pal
Fabrication Of Flexible, Biofunctional Architectures From Silk Proteins, Ramendra K. Pal
Theses and Dissertations
Advances in the biomedical field require functional materials and processes that can lead to devices that are biocompatible, and biodegradable while maintaining high performance and mechanical conformability. In this context, a current shift in focus is towards natural polymers as not only the structural but also functional components of such devices. This poses material-specific functionalization and fabrication related questions in the design and fabrication of such systems. Silk protein biopolymers from the silkworm show tremendous promise in this regard due to intrinsic properties: mechanical performance, optical transparency, biocompatibility, biodegradability, processability, and the ability to entrap and stabilize biomolecules. The unique …
Real-Time Biosensor For The Assessment Of Nanotoxicity And Cancer Electrotherapy, Evangelia Hondroulis
Real-Time Biosensor For The Assessment Of Nanotoxicity And Cancer Electrotherapy, Evangelia Hondroulis
FIU Electronic Theses and Dissertations
Knowledge of cell electronics has led to their integration to medicine either by physically interfacing electronic devices with biological systems or by using electronics for both detection and characterization of biological materials. In this dissertation, an electrical impedance sensor (EIS) was used to measure the electrode surface impedance changes from cell samples of human and environmental toxicity of nanoscale materials in 2D and 3D cell culture models. The impedimetric response of human lung fibroblasts and rainbow trout gill epithelial cells when exposed to various nanomaterials was tested to determine their kinetic effects towards the cells and to demonstrate the biosensor’s …