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Biomedical Engineering and Bioengineering Commons

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Medical Biophysics

Biomedical engineering

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Full-Text Articles in Biomedical Engineering and Bioengineering

A Quantitative Estimation Of Regulation And Transport Limitations In The Human Cardiopulmonary System , Sharmista Chatterjee Jan 1997

A Quantitative Estimation Of Regulation And Transport Limitations In The Human Cardiopulmonary System , Sharmista Chatterjee

Retrospective Theses and Dissertations

The object of this dissertation is to quantitatively describe the regulation of some of the exchange processes within the human body. Conceptually this dissertation is divided into two sections. In the first section a macroscopic view was adopted to describe the overall regulation of the cardiovascular and respiratory systems. These overall system models were used as heuristic tools to gain an understanding of physiological behavior in micro-gravity. In the second section, a microscopic view was used to estimate the role played by the surfactant system of the lung in regulating the transfer of fluid across the pulmonary-capillary wall;The basis ...


Water And Electrolyte Regulation During Space Flight And Exercise , Susan Elizabeth Doty Jan 1994

Water And Electrolyte Regulation During Space Flight And Exercise , Susan Elizabeth Doty

Retrospective Theses and Dissertations

When one is exposed to microgravity, fluid which is normally pooled in the lower extremities is redistributed headward and weight bearing bones begin to demineralize due to reduced mechanical stresses. The kidney, which is the primary regulator of body fluid volume and composition, responds to the fluid shift and bone demineralization by increasing the urinary output of water, sodium, and calcium. This research involves developing a mathematical description of how water and electrolytes are internally redistributed and exchanged with the environment during space flight. Various levels of activity are also considered, since it is believed that exercise can prevent some ...