Biomedical Engineering and Bioengineering Commons^™

Toward Translating Near-Infrared Spectroscopy Oxygen Saturation Data For The Non-Invasive Prediction Of Spatial And Temporal Hemodynamics During Exercise, Laura M. Ellwein, Margaret M. Samyn, Michael E. Danduran, Sheila M. Schindler-Ivens, Stacy Liebham, John F. Ladisa Jr.

Exercise Science Faculty Research and Publications

Image-based computational fluid dynamics (CFD) studies conducted at rest have shown that atherosclerotic plaque in the thoracic aorta (TA) correlates with adverse wall shear stress (WSS), but there is a paucity of such data under elevated flow conditions. We developed a pedaling exercise protocol to obtain phase contrast magnetic resonance imaging (PC-MRI) blood flow measurements in the TA and brachiocephalic arteries during three-tiered supine pedaling at 130, 150, and 170 % of resting heart rate (HR), and relate these measurements to non-invasive tissue oxygen saturation (StO₂) acquired by near-infrared spectroscopy (NIRS) while conducting the same protocol. Local quantification …