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Chemical Engineering

Amperometric

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Full-Text Articles in Biomedical Engineering and Bioengineering

Developing Electrochemical Biosensors For Point-Of-Care Diagnostics Of Cardiovascular Biomarkers, Yang Cheng Jan 2013

Developing Electrochemical Biosensors For Point-Of-Care Diagnostics Of Cardiovascular Biomarkers, Yang Cheng

Electronic Thesis and Dissertation Repository

Troponin is known as a type of reliable biomarker for the detection of cardiac disorders. Cardiac troponin I (cTnI), as a subunit of troponin, is highly sensitive to cardiac injury; therefore, the cTnI level is used as an index to diagnose myocardial damage, particularly acute myocardial infarction. It can be also used in cardiospecific diagnosis, risk stratification therapeutic treatment and post risk management. In this research, an amperometric immunosensor was developed based on planar electrode and sandwich ELISA format. The electrical response corresponding to biological information was obtained via four main procedures, including electrode modification, immunoreaction, signal amplifications and amperometric ...