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Full-Text Articles in Biomedical Engineering and Bioengineering
Synthesis And Characterization Of Magnetic Hydrogel Nanocomposites For Cancer Therapy Applications, Samantha Ann Meenach
Synthesis And Characterization Of Magnetic Hydrogel Nanocomposites For Cancer Therapy Applications, Samantha Ann Meenach
University of Kentucky Doctoral Dissertations
Currently, cancer is the second leading cause of death in the United States. Conventional cancer treatment includes chemotherapy, radiation, and surgical resection, but unfortunately, all of these methods have significant drawbacks. Hyperthermia, the heating of cancerous tissues to between 41 and 45°C, has been shown to improve the efficacy of cancer therapy when used in conjunction with irradiation and/or chemotherapy. In this work, a novel method for remotely administering heat is presented. This method involves heating of tumor tissue using hydrogel nanocomposites containing magnetic nanoparticles which can be remotely heated upon exposure to an external alternating magnetic field (AMF). The …