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Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
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- Biomaterials and Biosystems (4)
- Alumina (3)
- Alumina-Composite (3)
- Bioceramics (3)
- Biomaterials (3)
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- Functionally Graded Concept (3)
- Hydroxyapatite (3)
- Metal-ceramic functionally graded materials (3)
- Titanium (3)
- Zirconia (3)
- Barium titanate (2)
- Dental post (2)
- Dentistry (2)
- Denture base materials (2)
- Fracture toughness (2)
- Poly(methyl methacrylate) (2)
- Simulated body fluid (2)
- The influence of barium titanate filler on mechanical properties of denture base composite (2)
- Dental composite (1)
- Denture base composite (1)
- Human embryonic stem cell (1)
- Restoration (1)
- Ti-based fillers (1)
- Titanate coupling agent (1)
- Utilization of Ti-based fillers on denture base composite fabrication (1)
- Publication
Articles 1 - 10 of 10
Full-Text Articles in Biomedical Engineering and Bioengineering
Perspectives For Titanium-Derived Fillers Usage On Denture Base Composite Construction, Nidal Elshereksi
Perspectives For Titanium-Derived Fillers Usage On Denture Base Composite Construction, Nidal Elshereksi
Nidal Elshereksi
Poly(methyl methacrylate) (PMMA) is an extensively used material in dentistry because of its aesthetics, processability, and reparability. However, PMMA is still far from being ideal in fulfilling the mechanical requirements of prosthesis. PMMA-based denture base polymers exhibit low fracture resistance and radiopacity behavior. Efforts to improve the mechanical and radiopacity properties of denture base materials through inclusion of silica-based fillers are ongoing. Although silane-treated siliceous fillers are commonly used, they are not sufficiently strong.They also exhibit cracks, which either cut through the glass fillers or propagate around the filler particles. This defect occurs when the dental composites are placed in …
Microfabricated Nanotopological Surfaces For Study Of Adhesion-Dependent Cell Mechanosensitivity, Weiqiang Chen, Yubing Sun, Jianping Fu
Microfabricated Nanotopological Surfaces For Study Of Adhesion-Dependent Cell Mechanosensitivity, Weiqiang Chen, Yubing Sun, Jianping Fu
Weiqiang Chen
Cells exhibit high sensitivity and diverse responses to the intrinsic nanotopography of the extracellular matrix through their nanoscale cellular sensing machinery. A simple microfabrication method for precise control and spatial patterning of the local nanoroughness on glass surfaces by using photolithography and reactive ion etching is reported. It is demonstrated that local nanoroughness as a biophysical cue could regulate a diverse array of NIH/3T3 fi broblast behaviors, including cell morphology, adhesion, proliferation, migration, and cytoskeleton contractility. The capability to control and further predict cellular responses to nanoroughness might suggest novel methods for developing biomaterials mimicking nanotopographic structures in vivo for …
Surface-Micromachined Microfiltration Membranes For Efficient Isolation And Functional Immunophenotyping Of Subpopulations Of Immune Cells, Weiqiang Chen, Nien-Tsu Huang, Boram Oh, Raymond H. W. Lam, Rong Fan, Timothy T. Cornell, Thomas P. Shanley, Katsuo Kurabayashi, Jianping Fu
Surface-Micromachined Microfiltration Membranes For Efficient Isolation And Functional Immunophenotyping Of Subpopulations Of Immune Cells, Weiqiang Chen, Nien-Tsu Huang, Boram Oh, Raymond H. W. Lam, Rong Fan, Timothy T. Cornell, Thomas P. Shanley, Katsuo Kurabayashi, Jianping Fu
Weiqiang Chen
An accurate measurement of the immune status in patients with immune system disorders is critical in evaluating the stage of diseases and tailoring drug treatments. The functional cellular immunity test is a promising method to establish the diagnosis of immune dysfunctions. The conventional functional cellular immunity test involves measurements of the capacity of peripheral blood mononuclear cells to produce pro-inflammatory cytokines when stimulated ex vivo. However, this “bulk” assay measures the overall reactivity of a population of lymphocytes and monocytes, making it difficult to pinpoint the phenotype or real identity of the reactive immune cells involved. In this research, we …
Nanoroughened Surfaces For Efficient Capture Of Circulating Tumor Cells Without Using Capture Antibodies, Weiqiang Chen, Shinuo Weng, Feng Zhang, Steven Allen, Xiang Li, Liwei Bao, Raymond H. W. Lam, Jill A. Macoska, Sofia D. Merajver, Jianping Fu
Nanoroughened Surfaces For Efficient Capture Of Circulating Tumor Cells Without Using Capture Antibodies, Weiqiang Chen, Shinuo Weng, Feng Zhang, Steven Allen, Xiang Li, Liwei Bao, Raymond H. W. Lam, Jill A. Macoska, Sofia D. Merajver, Jianping Fu
Weiqiang Chen
Circulating tumor cells (CTCs) detached from both primary and metastatic lesions represent a potential alternative to invasive biopsies as a source of tumor tissue for the detection, characterization and monitoring of cancers. Here we report a simple yet effective strategy for capturing CTCs without using capture antibodies. Our method uniquely utilized the differential adhesion preference of cancer cells to nanorough surfaces when compared to normal blood cells and thus did not depend on their physical size or surface protein expression, a significant advantage as compared to other existing CTC capture techniques.
Nanotopography Influences Adhesion, Spreading, And Self-Renewal Of Human Embryonic Stem Cells, Weiqiang Chen, Luis G. Villa-Diaz, Yubing Sun, Shinuo Weng, Jin Koo Kim, Raymond H. W. Lam, Lin Han, Rong Fan, Paul H. Krebsbach, Jianping Fu
Nanotopography Influences Adhesion, Spreading, And Self-Renewal Of Human Embryonic Stem Cells, Weiqiang Chen, Luis G. Villa-Diaz, Yubing Sun, Shinuo Weng, Jin Koo Kim, Raymond H. W. Lam, Lin Han, Rong Fan, Paul H. Krebsbach, Jianping Fu
Weiqiang Chen
Human embryonic stem cells (hESCs) have great potentials for future cell-based therapeutics. However, their mechanosensitivity to biophysical signals from the cellular microenvironment is not well characterized. Here we introduced an effective microfabrication strategy for accurate control and patterning of nanoroughness on glass surfaces. Our results demonstrated that nanotopography could provide a potent regulatory signal over different hESC behaviors, including cell morphology, adhesion, proliferation, clonal expansion, and self-renewal. Our results indicated that topological sensing of hESCs might include feedback regulation involving mechanosensory integrin-mediated cell matrix adhesion, myosin II, and E-cadherin. Our results also demonstrated that cellular responses to nanotopography were cell-type …
A New Multilayer Composite With Functionally Graded Design For Endodontic Application., Ahmed A. Madfa
A New Multilayer Composite With Functionally Graded Design For Endodontic Application., Ahmed A. Madfa
Ahmed A. Madfa
Multilayer composite with FG structure were fabricated using zirconia (ZrO), alumina (AI2O3), Hydroxyapatite (HA) and titanium (Ti) micropowders. Powder selection and their combination in each layer were according to the results of finite element analysis.
Microstructural Characteristics Of Functionally Graded Materials Designed As Dental Post, Ahmed A. Madfa
Microstructural Characteristics Of Functionally Graded Materials Designed As Dental Post, Ahmed A. Madfa
Ahmed A. Madfa
To study the interfaces and microstructure of multilayered materials fabricated based on functionally graded concept for use as dental posts.
New Generation Of The Dental Posts For Endodontic Application., Ahmed A. Madfa
New Generation Of The Dental Posts For Endodontic Application., Ahmed A. Madfa
Ahmed A. Madfa
Fabricated multilayer dental post with the functionally graded design is a novel product that exhibits graded properties varied from coronal to apical parts of the tooth. The new dental post definitely performs better than posts available in the market and improves the quality of human life
Effect Of Filler Incorporation On The Fracture Toughness Properties Of Denture Base Poly(Methyl Methacrylate), Nidal Elshereksi
Effect Of Filler Incorporation On The Fracture Toughness Properties Of Denture Base Poly(Methyl Methacrylate), Nidal Elshereksi
Nidal Elshereksi
Poly(methyl methacrylate) (PMMA) is the material of choice for denture base construction. In spite of its many good qualities, the application of PMMA as an ideal dental base material is still restricted by a few limitations. One of these is the difficulty in achieving intrinsic radiopacity in the material. The aim of the present study is to investigate the possibility of using barium titanate (BaTiO3) as a radiopacifier in PMMA. The formulation used in this study composed of PMMA 89.5 wt%, BaTiO3 10 wt% and benzoyl peroxide (BPO) 0.5 wt% as an initiator, methyl methacrylate (MMA) 90 wt% as a …
Effect Of Filler Incorporation On The Fracture Toughness Properties Of Denture Base Poly(Methyl Methacrylate), Nidal Elshereksi
Effect Of Filler Incorporation On The Fracture Toughness Properties Of Denture Base Poly(Methyl Methacrylate), Nidal Elshereksi
Nidal Elshereksi
Poly(methyl methacrylate) (PMMA) is the material of choice for denture base construction. In spite of its many good qualities, the application of PMMA as an ideal dental base material is still restricted by a few limitations. One of these is the difficulty in achieving intrinsic radiopacity in the material. The aim of the present study is to investigate the possibility of using barium titanate (BaTiO3) as a radiopacifier in PMMA. The formulation used in this study composed of PMMA 89.5 wt%, BaTiO3 10 wt% and benzoyl peroxide (BPO) 0.5 wt% as an initiator, methyl methacrylate (MMA) 90 wt% as a …