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Chemical engineering

2006

Life Sciences

Articles 1 - 3 of 3

Full-Text Articles in Engineering

Computational Methods In The Study Of Carbohydrates And Carbohydrate-Active Enzymes , Anthony David Hill Jan 2006

Computational Methods In The Study Of Carbohydrates And Carbohydrate-Active Enzymes , Anthony David Hill

Retrospective Theses and Dissertations

Carbohydrates are important molecules in energy storage and cellular recognition. New methods are used and discussed to capture important structural details of created by the protein/carbohydrate interactions. In particular, the thermodynamics of carbohydrate binding are explored, and a new model to accurately calculate the free energy of binding is developed. Additionally, a new method of describing the pucker of carbohydrate ring with three coordinates is discussed. These methods are then applied to Family 1 Glycoside Hydrolases.


Carbon-13 Metabolic Flux Analysis Of Soybean Central Carbon Metabolism: Response To Temperature And Genotype Effects , Vidya Vaancheeswaran Iyer Jan 2006

Carbon-13 Metabolic Flux Analysis Of Soybean Central Carbon Metabolism: Response To Temperature And Genotype Effects , Vidya Vaancheeswaran Iyer

Retrospective Theses and Dissertations

Soybeans are a major source of high quality protein, edible oil, food products, and also several industrial non food applications such as paper coating, textiles and plastics. It is difficult to develop soybeans with high protein and high oil, however, due to the inverse relationship between these two components. Consequently, increasing seed protein concentration without adversely affecting the yield and oil content has been difficult to achieve. It has been demonstrated that the temperature and genotype of soybeans influence the protein or lipid composition considerably. However, the interactions between various pathways responsible for the changes in the composition are unknown ...


Directed Growth And Selective Differentiation Of Neural Progenitor Cells Using A Synergistic Combination Of Topographical And Soluble Cues , Jennifer Behr Recknor Jan 2006

Directed Growth And Selective Differentiation Of Neural Progenitor Cells Using A Synergistic Combination Of Topographical And Soluble Cues , Jennifer Behr Recknor

Retrospective Theses and Dissertations

The purpose of this study is to develop strategies to facilitate nerve regeneration using a synergistic combination of guidance cues. We are investigating the cellular mechanisms of development using adult rat hippocampal progenitor cells (AHPCs) and have demonstrated that manipulating a combination of physical, chemical and biological cues can lead to oriented astrocyte and neural progenitor cell outgrowth and can influence progenitor cell differentiation. To provide physical guidance, micropatterned polystyrene (PS) substrates were fabricated and chemically modified with laminin. Astrocytes or AHPCs cultured on these substrates align along the grooves of the patterned surface extending highly elongated processes. To further ...