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Articles 1 - 7 of 7
Full-Text Articles in Engineering
Understanding Conformational Regulation Of The Integrin I-Domain For Design Of Chimeric Protein Switches, Niall Phelan Terry, Liang Fang, J Vincent Price, Eric T. Boder Dr.
Understanding Conformational Regulation Of The Integrin I-Domain For Design Of Chimeric Protein Switches, Niall Phelan Terry, Liang Fang, J Vincent Price, Eric T. Boder Dr.
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
Within all complex biological processes intricate proteins are expressed to complete every niche and necessary task. Many express multiple allosterically regulated conformational states, with protein function regulated by effector molecules and other ligands. One such protein is the LFA-1 surface integrin protein and its inserted domain, the I-domain. We Isolated the I-domain for investigation of determining binding properties and understanding conformational regulations of affinity changes to its target ligand ICAM-1, for further use in chimeric protein switch design. A large change in binding affinity was found through the deletion of a sub-sequence of amino acids in I-domain known as the …
Elucidating Growth Coupling Of Metabolites In E. Coli And Characterizing Modularity., Preston N. Nicely
Elucidating Growth Coupling Of Metabolites In E. Coli And Characterizing Modularity., Preston N. Nicely
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
This project seeks to increase the efficiency of rapid engineering strain design by elucidating the functionality of a modular cell. The modular cell theory insinuates that there exists a baseline cellular framework from which cellular products can be produced by inserting a designed production module into the cell. In this study, recombinant gene cloning techniques were used to design metabolite production modules that focused on increasing the production, titer, and yield of ethanol and lactate within Escherichia coli (E. coli). An auxotrophic chassis cell was created by ModCell2 and multi-objective strain design to determine the genes necessary for deletion. The …
The Effect Of Flinak Molten Salt Corrosion On The Hardness Of Hastelloy N, David Kok
The Effect Of Flinak Molten Salt Corrosion On The Hardness Of Hastelloy N, David Kok
Scholar Week 2016 - present
The Molten Salt Reactor (MSR) has been identified as a promising candidate to replace aging nuclear reactors around the world. However, a suitable combination of molten salt and container material needs to be found in order to reduce the potential for corrosion in the MSR before it can be considered commercially viable. FLiNaK molten salt and the nickel-based alloy Hastelloy N have been identified as prime candidates for this function, but the severity of FLiNaK corrosion in Hastelloy N requires additional study before this combination can be used in the operation of a MSR. In this study, Hastelloy N samples …
Cnt-Tio2 Composites For Photocatalytic Oxidation Of Atmospheric Pollutants, Alison Chan
Cnt-Tio2 Composites For Photocatalytic Oxidation Of Atmospheric Pollutants, Alison Chan
Kansas State University Undergraduate Research Conference
The design of catalysts for growth of carbon nanotubes is studied to develop recipes and mechanisms for controlled and scalable growth of carbon nanotubes (CNTs). The objective of the study is to tune the photocatalytic properties of titanium dioxide (TiO₂) by coupling to multiwalled carbon nanotubes (MWNTs). Multiwalled CNTs have been shown to act as an electron sink when coupled with TiO2, thereby inhibiting electron-hole recombination and enhancing photocatalytic degradation of environmental pollutants. A test using acetaldehyde confirmed our findings in the field, where the loading ratio of 99 wt% TiO2 (1 wt% CNTs) has a high …
Expression And Purification Of Hfb1 From The Bacterial Host Escherchia Coli, Jose Cardenas-Perez
Expression And Purification Of Hfb1 From The Bacterial Host Escherchia Coli, Jose Cardenas-Perez
Kansas State University Undergraduate Research Conference
Hydrophobins are a unique class of proteins which grow in fungi which demonstrate unique properties, such as self-assembly into two dimensional arrays at water/air or water/solid interfaces. A specific type of hydrophobins, HFB1, will be closely examined, expressed, and purified within an e. coli host. Most hydrophobins are used within the medical field and are harvested directly from the fungi, with little research done to express the protein within a bacterial host for large scale production. Our research will revolve around developing a method to clone, express, and purify the hydrophobin, HFB1, within the bacterial host, with tweaking of the …
Introducing Concept Maps In Undergraduate Thermodynamics, Jessie Lofton
Introducing Concept Maps In Undergraduate Thermodynamics, Jessie Lofton
ASEE IL-IN Section Conference
Concept maps, also called mind maps, are a widely utilized educational tool. While numerous studies cite the benefits of concept mapping as a tool for student learning, the use of concept maps is more common in non-engineering disciplines. This study examines student perceptions and academic performance in an undergraduate, introductory Thermodynamics course for students majoring in Mechanical Engineering. The pedagogical approach includes incorporating student-developed concept maps, as well as an interactive study tool for First Law analysis. Qualitative and quantitative results are presented. Results are limited to a single institution and a small sample size of students. Future work will …
Use Of Penetrating Asphalt Emulsions To Address High-Void Pavement Areas, Andrew Eicher, Curt Higginbotham
Use Of Penetrating Asphalt Emulsions To Address High-Void Pavement Areas, Andrew Eicher, Curt Higginbotham
Purdue Road School
Longitudinal joints are high in air voids due to compaction limitations. Lowering the void content of these areas improves the durability of the pavement. Project data indicate that rapid penetrating emulsion (RPE) fills the voids beneath the surface of the pavement, reducing air and water intrusion while maintaining surface texture, whereas traditional emulsions seal the surface only. Lab tests have been developed to quantify the penetrating ability of an emulsion and resistance to water exposure. Join us for a discussion.