- Gait (2)
- Bioorthogonal (1)
- Object Transport (1)
- Manual Control (1)
- Dual Task (1)
- Coordination Variability (1)
- Nanoimprint Lithography; Inkjet-printing; Glucose Sensor; Cortisol Sensor; Microfluidics; Lithium-ion Electrode (1)
- Exoskeleton (1)
- Hybridization chain reaction (1)
- Intrinsic Dynamics (1)
- Antibiotics (1)
- Prosthesis (1)
- Nanomaterials (1)
- Multi-drug resistance (1)
- Predictive simulation (1)
- DNA nanotechnology (1)
- Living polymerization (1)
- Drug-delivery (1)
- Cost function (1)
- Bacterial biofilms (1)
- Walking (1)
- Coordination (1)
Articles 1 - 5 of 5
Full-Text Articles in Engineering
Predictive Simulation Of Human Movement And Applications To Assistive Device Design And Control, Vinh Nguyen
Predictive simulation based on dynamic optimization using musculoskeletal models is a powerful approach for studying biomechanics of human gait. Predictive simulation can be used for a variety of applications from designing assistive devices to testing theories of motor controls. However, one of the challenges in formulating the predictive dynamic optimization problem is that the cost function, which represents the underlying goal of the walking task (e.g., minimal energy consumption) is generally unknown and is assumed a priori. While different studies used different cost functions, the qualities of the gaits with those cost functions were often not provided. Therefore, this ...
Bioinspired Complex Nanoarchitectures By Dna Supramolecular Polymerization, Laura A. Lanier
Bioinspired nanoarchitectures are of great interest for applications in fields such as nanomedicine, tissue engineering, and biosensing. With this interest, understanding how the physical properties of these complex nanostructures relate to their function is increasingly important. This dissertation describes the creation of complex nanoarchitectures with controlled structure and the investigation of the effect of nanocarrier physical properties on cell uptake for applications in nanomedicine.
DNA self-assembly by supramolecular polymerization was chosen to create complex nanostructures of controlled architectures. We demonstrated that the supramolecular polymerization of DNA known as hybridization chain reaction (HCR) is in fact a living polymerization. The living ...
Engineering Nanomaterials For Imaging And Therapy Of Bacteria And Biofilm-Associated Infections, Akash Gupta
Infections caused by multidrug-resistant (MDR) bacteria pose a serious global burden of mortality, causing thousands of deaths each year. The “superbug” risk is further exacerbated by chronic infections generated from antibiotic-resistant biofilms that are highly resistant to available treatments. Synthetic macromolecules such as polymers and nanoparticles have emerged as promising antimicrobials. Moreover, ability to modulate nanomaterial interaction with bacterial cellular systems plays a pivotal role in improving the efficacy of the strategy.
In the initial studies on engineering nanoparticle surface chemistry, I investigated the role played by surface ligands in determining the antimicrobial activity of the nanoparticles. In further study ...
Walking For Object Transport: An Examination Of The Coordinative Adaptations To Locomotor, Perceptual, And Manual Task Constraints, Avelino Amado
The goal of this dissertation was to understand how the intrinsic dynamics of gait adapt to support the performance of an ecologically relevant object transport task. A common object transport task is walking with a cup of water. Because the water can move relatively independent of the cup, the cup and water system is classified as a complex object. To model this task participants carried a cup with a wooden lid placed on top. On the lid there was a circular region with the same circumference as the cup and a ball. The object of the task was to keep ...
Direct Printing/Patterning Of Key Components For Biosensor Devices, Yiliang Zhou
Recently, biosensor devices, especially wearable devices for monitoring human health, have attracted significant interests and meanwhile, they have a huge market. These wearable biosensor devices usually consist of several key components, including microfluidics, biosensing elements and power supply. Though advanced sensing platforms have been extensively explored, high manufacturing fee and lack of practical functions are the main reasons that most of devices and techniques are still out of reach for potential users.
This dissertation focuses on fabricating these key components for biosensor devices via advanced printing/patterning techniques, such as inkjet-printing and nanoimprinting. These fabrication techniques can be potentially extended ...