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Full-Text Articles in Engineering

Polyball: A New Adsorbent For The Efficient Removal Of Endotoxin From Biopharmaceuticals, Sidharth Razdan, Jee-Ching Wang, Sutapa Barua Dec 2019

Polyball: A New Adsorbent For The Efficient Removal Of Endotoxin From Biopharmaceuticals, Sidharth Razdan, Jee-Ching Wang, Sutapa Barua

Chemical and Biochemical Engineering Faculty Research & Creative Works

The presence of endotoxin, also known as lipopolysaccharides (LPS), as a side product appears to be a major drawback for the production of certain biomolecules that are essential for research, pharmaceutical, and industrial applications. In the biotechnology industry, gram-negative bacteria (e.g., Escherichia coli ) are widely used to produce recombinant products such as proteins, plasmid DNAs and vaccines. These products are contaminated with LPS, which may cause side effects when administered to animals or humans. Purification of LPS often suffers from product loss. For this reason, special attention must be paid when purifying proteins aiming a product as free as ...


Advanced Measurement Techniques For Enabling Multiphase Reactors And Flow Systems For Sustainable And Cleaner Processes, Muthanna H. Al-Dahhan Jul 2019

Advanced Measurement Techniques For Enabling Multiphase Reactors And Flow Systems For Sustainable And Cleaner Processes, Muthanna H. Al-Dahhan

Chemical and Biochemical Engineering Faculty Research & Creative Works

No abstract provided.


Method Of Forming Microparticles For Use In Cell Seeding, Sutapa Barua, Chase Herman Jun 2019

Method Of Forming Microparticles For Use In Cell Seeding, Sutapa Barua, Chase Herman

Chemical and Biochemical Engineering Faculty Research & Creative Works

The present invention is directed to methods for forming microparticles useful for cell seeding and for conjugating protein to the surface of the microparticles. The method comprises co-injecting an organic solution of PLGA or other polymer with an aqueous solution into a flow focusing tube.


Slightly Fluorination Of Al₂O₃ Ald Coating On Li₁.₂Mn₀.₅₄Coo.₁₃Ni₀.₁₃O₂ Electrodes: Interface Reaction To Create Stable Solid Permeable Interphase Layer, Han Yu, Yan Gao, Xinhua Liang Jun 2019

Slightly Fluorination Of Al₂O₃ Ald Coating On Li₁.₂Mn₀.₅₄Coo.₁₃Ni₀.₁₃O₂ Electrodes: Interface Reaction To Create Stable Solid Permeable Interphase Layer, Han Yu, Yan Gao, Xinhua Liang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Improving the performance of cathodes by using surface coatings has proven to be an effective method for improving the stability of Li-ion batteries (LIBs), while a high-quality film satisfying all requirements of electrochemical inertia, chemical stability, and lithium ion conductivity has not been found. In this study, a composite film composed of Al2O3 and AlF3 layers was coated on the surface of Li1.2Mn0.54Co0.13Ni0.13O2 (Li-rich NMC) based electrodes by atomic layer deposition (ALD). By varying the ratio of Al2O3 and AlF ...


Revisiting The Butler-Mokrys Model For The Vapor-Extraction Process, Vijitha Mohan, Partho Neogi, Baojun Bai Apr 2019

Revisiting The Butler-Mokrys Model For The Vapor-Extraction Process, Vijitha Mohan, Partho Neogi, Baojun Bai

Chemical and Biochemical Engineering Faculty Research & Creative Works

The dynamics of a process in which a solvent in the form of a vapor or gas is introduced in a heavy-oil reservoir is considered. The process is called the solvent vapor-extraction process (VAPEX). When the vapor dissolves in the oil, it reduces its viscosity, allowing oil to flow under gravity and be collected at the bottom producer well. The conservation-of-species equation is analyzed to obtain a more-appropriate equation that differentiates between the velocity within the oil and the velocity at the interface, which can be solved to obtain a concentration profile of the solvent in oil. We diverge from ...


3d Printed Zeolite Monoliths For Co₂ Removal, Fateme Rezaei, Harshul V. Thakkar Mar 2019

3d Printed Zeolite Monoliths For Co₂ Removal, Fateme Rezaei, Harshul V. Thakkar

Chemical and Biochemical Engineering Faculty Research & Creative Works

Carbon dioxide (CO2) capture materials comprising one or more 3D-printed zeolite monoliths for the capture and or removal of CO2 from air or gases in enclosed compartments, including gases or mixtures of gases having less than about 5% CO2. Methods for preparing 3D-printed zeolite monoliths useful as CO2 capture materials and filters, as well as methods of removing CO2 from a gas or mixture of gases in an enclosed compartment using 3D-printed zeolite monoliths are provided.


Cutter Elements For Drill Bits And Methods For Fabricating Same, Guodong Zhan, Biju P. Kumar, Russell C. Gilleylen, Michael D. Hughes, Xinhua Liang Feb 2019

Cutter Elements For Drill Bits And Methods For Fabricating Same, Guodong Zhan, Biju P. Kumar, Russell C. Gilleylen, Michael D. Hughes, Xinhua Liang

Chemical and Biochemical Engineering Faculty Research & Creative Works

A method of fabricating a PCD cutter element including a diamond table including a plurality of coated diamond particles fabricated using an atomic layer deposition (ALD) process.


Cutter Elements For Drill Bits And Methods For Fabricating Same, Guodong Zhan, Biju Pillai Kumar, Russell C. Gilleylen, Michael D. Hughes, Xinhua Liang Feb 2019

Cutter Elements For Drill Bits And Methods For Fabricating Same, Guodong Zhan, Biju Pillai Kumar, Russell C. Gilleylen, Michael D. Hughes, Xinhua Liang

Chemical and Biochemical Engineering Faculty Research & Creative Works

A method of fabricating a PCD cutter element including a diamond table including a plurality of coated diamond particles fabricated using an atomic layer deposition (ALD) process.


Zeolitic 3d Scaffolds With Tailored Surface Topography For Methanol Conversion With Light Olefins Selectivity, Ali A. Rownaghi, Xin Li, Fateme Rezaei Jan 2019

Zeolitic 3d Scaffolds With Tailored Surface Topography For Methanol Conversion With Light Olefins Selectivity, Ali A. Rownaghi, Xin Li, Fateme Rezaei

Chemical and Biochemical Engineering Faculty Research & Creative Works

The present disclosure relates to 3D printed zeolite scaffolds . The zeolite scaffolds can be used as a catalyst for methanol to olefin ( MTO ) conversion and hydrocarbon cracking processes.


Modeling Cell Line-Specific Recruitment Of Signaling Proteins To The Insulin-Like Growth Factor 1 Receptor, Keesha E. Erickson, Dipak Barua, For Full List Of Authors, See Publisher's Website. Jan 2019

Modeling Cell Line-Specific Recruitment Of Signaling Proteins To The Insulin-Like Growth Factor 1 Receptor, Keesha E. Erickson, Dipak Barua, For Full List Of Authors, See Publisher's Website.

Chemical and Biochemical Engineering Faculty Research & Creative Works

Receptor tyrosine kinases (RTKs) typically contain multiple autophosphorylation sites in their cytoplasmic domains. Once activated, these autophosphorylation sites can recruit downstream signaling proteins containing Src homology 2 (SH2) and phosphotyrosine-binding (PTB) domains, which recognize phosphotyrosine-containing short linear motifs (SLiMs). These domains and SLiMs have polyspecific or promiscuous binding activities. Thus, multiple signaling proteins may compete for binding to a common SLiM and vice versa. To investigate the effects of competition on RTK signaling, we used a rule-based modeling approach to develop and analyze models for ligand-induced recruitment of SH2/PTB domain-containing proteins to autophosphorylation sites in the insulin-like growth factor ...


Effects Of Mixing Methods Of Bifunctional Catalysts On Catalyst Stability Of Dme Synthesis Via Co₂ Hydrogenation, Shoujie Ren, Shiguang Li, Naomi Klinghoffer, Miao Yu, Xinhua Liang Jan 2019

Effects Of Mixing Methods Of Bifunctional Catalysts On Catalyst Stability Of Dme Synthesis Via Co₂ Hydrogenation, Shoujie Ren, Shiguang Li, Naomi Klinghoffer, Miao Yu, Xinhua Liang

Chemical and Biochemical Engineering Faculty Research & Creative Works

The effects of three different mixing methods of CuO/ZnO/Al2O3 (CZA) and HZSM-5 bifunctional catalyst on the stability for dimethyl ether (DME) synthesis from carbon dioxide (CO2) hydrogenation were investigated. When the bifunctional catalyst was prepared by method A (mixing powder without pelletization), there was no significant change in DME production and catalyst stability when the HZSM-5 loading was varied between 0.1 g and 0.5 g with a fixed CZA loading of 0.5 g,. When the bifunctional catalysts were prepared by method B (pressed into pellets of CZA and pellets of HZSM-5 ...