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A Study Of Brain Neuronal And Functional Complexities Estimated Using Multiscale Entropy In Healthy Young Adults, Sreevalsan S. Menon, K. Krishnamurthy
A Study Of Brain Neuronal And Functional Complexities Estimated Using Multiscale Entropy In Healthy Young Adults, Sreevalsan S. Menon, K. Krishnamurthy
Mechanical and Aerospace Engineering Faculty Research & Creative Works
Brain complexity estimated using sample entropy and multiscale entropy (MSE) has recently gained much attention to compare brain function between diseased or neurologically impaired groups and healthy control groups. Using resting-state functional magnetic resonance imaging (rfMRI) blood oxygen-level dependent (BOLD) signals in a large cohort (n = 967) of healthy young adults, the present study maps neuronal and functional complexities estimated by using MSE of BOLD signals and BOLD phase coherence connectivity, respectively, at various levels of the brain’s organization. The functional complexity explores patterns in a higher dimension than neuronal complexity and may better discern changes in brain functioning. …