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2019

City University of New York (CUNY)

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Articles 31 - 44 of 44

Full-Text Articles in Engineering

Bioelectrical Circuits: Lecture 7, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 7, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Bioelectrical Circuits: Lecture 1, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 1, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Bioelectrical Circuits: Lecture 3, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 3, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Bioelectrical Circuits: Lecture 4, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 4, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Bioelectrical Circuits: Lecture 5, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 5, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Bioelectrical Circuits: Lecture 8, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 8, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Bioelectrical Circuits: Lecture 6, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 6, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Bioelectrical Circuits: Lecture 2, Jacek P. Dmochowski, Luis Cardoso Jan 2019

Bioelectrical Circuits: Lecture 2, Jacek P. Dmochowski, Luis Cardoso

Open Educational Resources

No abstract provided.


Msg-Fast: Metagenomic Shotgun Data Fast Annotation Using Microbial Gene Catalogs, Stuart M. Brown, Hao Chen, Yuhan Hao, Bobby P. Laungani, Thahmina A. Ali, Changsu Dong, Carlos Lijeron, Baekdoo Kim, Claudia Wultsch, Zhiheng Pei, Konstantinos Krampis Jan 2019

Msg-Fast: Metagenomic Shotgun Data Fast Annotation Using Microbial Gene Catalogs, Stuart M. Brown, Hao Chen, Yuhan Hao, Bobby P. Laungani, Thahmina A. Ali, Changsu Dong, Carlos Lijeron, Baekdoo Kim, Claudia Wultsch, Zhiheng Pei, Konstantinos Krampis

Publications and Research

Background: Current methods used for annotating metagenomics shotgun sequencing (MGS) data rely on a computationally intensive and low-stringency approach of mapping each read to a generic database of proteins or reference microbial genomes.

Results: We developed MGS-Fast, an analysis approach for shotgun whole-genome metagenomic data utilizing Bowtie2 DNA-DNA alignment of reads that is an alternative to using the integrated catalog of reference genes database of well-annotated genes compiled from human microbiome data. This method is rapid and provides high-stringency matches (>90% DNA sequence identity) of the metagenomics reads to genes with annotated functions. We demonstrate the use of this method ...


Ict-Enabled Control And Energy Management Of Community Microgrids For Resilient Smart Grid Operation, Mahmoud Saleh Jan 2019

Ict-Enabled Control And Energy Management Of Community Microgrids For Resilient Smart Grid Operation, Mahmoud Saleh

Dissertations and Theses

Our research has focused on developing novel controllers and algorithms to enhance the resilience of the power grid and increase its readiness level against major disturbances.

The U.S. power grid currently encounters two main challenges: (1) the massive and extended blackouts caused by natural disasters, such as hurricane Sandy. These blackouts have raised a national call to explore innovative approaches for enhanced grid resiliency. Scrutinizing how previous blackouts initiated and propagated throughout the power grid, the major reasons are lack of situational awareness, lack of real-time monitoring and control, underdeveloped controllers at both the transmission and distribution levels, and ...


Translational Modeling Of Non-Invasive Electrical Stimulation, Dennis Quangvinh Truong Jan 2019

Translational Modeling Of Non-Invasive Electrical Stimulation, Dennis Quangvinh Truong

Dissertations and Theses

Seminal work in the early 2000’s demonstrated the effect of low amplitude non-invasive electrical stimulation in people using neurophysiological measures (motor evoked potentials, MEPs). Clinical applications of transcranial Direct Current Stimulation (tDCS) have since proliferated, though the mechanisms are not fully understood. Efforts to refine the technique to improve results are on-going as are mechanistic studies both in vivo and in vitro. Volume conduction models are being applied to these areas of research, especially in the design and analysis of clinical montages. However, additional research on the parameterization of models remains.

In this dissertation, Finite Element Method (FEM) models ...


Neuron-Glial (Ng) Interactions: A Microfluidic Examination Of Ng Emergent Responses For Repair, Tanya Singh Jan 2019

Neuron-Glial (Ng) Interactions: A Microfluidic Examination Of Ng Emergent Responses For Repair, Tanya Singh

Dissertations and Theses

Neuron-glia communication is crucial to the development, plasticity, and repair of the nervous system (NS). While neurons are well known to conduct electrical impulses that transfer biological information and stimuli throughout the NS, our understanding of the roles of glia continues to evolve from when the cells were largely believed to act solely for neuronal support. Recent decades of research has shown that glia can alter metabolism, conduct impulses and change phenotype for NS repair. NG interactions have, thereby, become heavily researched in varied areas of biomedical engineering, including embryogenesis, neural regeneration, growth, and intracellular synaptic activity. However, while NG ...


Modification Of Lipid Microenvironments On Solid Support Structures For Use In Transmembrane Protein Assays, William J. Houlihan Jan 2019

Modification Of Lipid Microenvironments On Solid Support Structures For Use In Transmembrane Protein Assays, William J. Houlihan

Dissertations and Theses

Gamma-Secretase (γ-secretase) is a transmembrane protease of increasing interest, which has been shown to have significant connections to both cancer and Alzheimer’s disease. γ-secretase cleaves both Notch-1, a transmembrane signaling protein, and Amyloid precursor protein (APP), a transmembrane protein whose cleavage may result in the formation of β-amyloid plaques in the brain. Notch-1 and APP are widely studied proteins that have substantial impacts on the development and proliferation of cancer and Alzheimer’s disease, respectively. Notch-1 partakes in the signaling of apoptosis in damaged and mutated cells, thus its cleavage by γ-secretase within the plasma membrane has ramifications on ...


Controlled Migration Of Retinal Progenitor Cells Within Electro-Chemotactic Fields, Shawn Mishra Jan 2019

Controlled Migration Of Retinal Progenitor Cells Within Electro-Chemotactic Fields, Shawn Mishra

Dissertations and Theses

Vision loss in retinal degenerative diseases is overwhelmingly attributed to damage and death of retinal photoreceptor cells. Studies in mouse retina have suggested that transplantation of isolated post-natal or stem cell-derived retinal progenitor cells (RPCs) to replace apoptotic or damaged photoreceptors may be a novel approach to restore vision. Thus far, outcomes project that the amount of restored visual response depends upon the migration of transplanted cells from insertion in the sub-retinal space to the outer nuclear layer (ONL). However, transplantation efficiency is exceedingly low – ~5% cells transplanted enter the retina – directly limiting the efficacy of the treatments. Additionally, the ...