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Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

2019

City University of New York (CUNY)

Medicine and Health Sciences

Fabrication

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Full-Text Articles in Engineering

Fabrication And Imaging Characterization Of Poly (Dimethyl Siloxane)/Sic Nano-Fillers Samples As Model Biomaterials, Tetiana Soloviova, Viorica Gutu, Zoya Vinokur, Akm S. Rahman, Subhendra Sarkar Dec 2019

Fabrication And Imaging Characterization Of Poly (Dimethyl Siloxane)/Sic Nano-Fillers Samples As Model Biomaterials, Tetiana Soloviova, Viorica Gutu, Zoya Vinokur, Akm S. Rahman, Subhendra Sarkar

Publications and Research

Biopolymers are being developed with embedded nanostructures for in vivo drug delivery to treat various diseases including cancers. In the current project we developed fabrication steps to prepare two biopolymers, poly di-methoxy siloxane (PDMS) with 0-0.9 vol% of SiC nano whisker (fillers) followed by non- destructive characterization. Optical reflection microscopy (5-100X) was performed to ensure loading and distribution of increasing SiC content. Optical microscopy showed progressively higher SiC distribution as filler loading was increased from 0-0.9 vol%. X-ray imaging at low kV (kilovoltage) and low mAs (milliamperage per second) were optimized to allow distinction between filled PDMS with SiC concentration …