Engineering Commons^™

Alternative Models Of Connectivity: Reclaiming Networked Spaces, Philip M. Bain

Electronic Theses and Dissertations

Alternative networking is a growing field of study and practice due to advancements in computer networking hardware, and software protocols. Methods of integrating alternative networking configurations into infrastructure present enhanced forms of empowerment and embodiment for participants. Through an analysis of multiple hardware and software examples, this research suggests that practices of sharing and collaboration, which are embedded in the history of computer networking, have the potential to reinvigorate the notion of a virtual public sphere, and support the ideals of digital democracy.

Fibroblast-Derived Extracellular Matrix: An Alternative Cell Culture Substrate That Alters Lung Cancer Cell Line Phenotype., Michael Thomas Scherzer

Electronic Theses and Dissertations

Poor lung cancer survival can largely be contributed to the metastatic cells that invade and spread throughout the body. The tumor microenvironment (TME) is composed of multiple cell types, as well as non-cellular components. The TME plays a critical role in the development of metastatic cancers by providing migratory cues that change the growing tumor’s properties. The Extracellular Matrix (ECM), a main component of the TME, has been shown to change composition during tumor progression, allowing cancer cells to invade tissue and survive away from the primary cancer site. Although the ECM is well-known to influence the fate of tumor …

Vanadium Trichloride Thermochemical Solar Energy Storage System Analysis., Caleb Michael Rogers

Electronic Theses and Dissertations

As annual energy consumption grows, developing renewable solar energy conversion systems, storage systems, and high density electrical energy production systems is growing increasingly important. The proposed system utilizes vanadium trichloride thermal decomposition to produce chlorine gas and vanadium dichloride. A second reaction combines gaseous hydrogen chloride and the product vanadium dichloride to reform vanadium trichloride and produce hydrogen gas. Hydrogen gas and chlorine gas can be stored indefinitely and electrical energy is obtained from the chemicals by a non-humidified dry membrane hydrogen – chlorine fuel cell. The fuel cell produces the gaseous hydrogen chloride needed to reform vanadium trichloride. The …

Shape Analysis Of The Human Brain., Matthew Joseph Nitzken 1987-

Electronic Theses and Dissertations

Autism is a complex developmental disability that has dramatically increased in prevalence, having a decisive impact on the health and behavior of children. Methods used to detect and recommend therapies have been much debated in the medical community because of the subjective nature of diagnosing autism. In order to provide an alternative method for understanding autism, the current work has developed a 3-dimensional state-of-the-art shape based analysis of the human brain to aid in creating more accurate diagnostic assessments and guided risk analyses for individuals with neurological conditions, such as autism. Methods: The aim of this work was to assess …

A Forensics Software Toolkit For Dna Steganalysis., Marc Bjoern Beck

Electronic Theses and Dissertations

Recent advances in genetic engineering have allowed the insertion of artificial DNA strands into the living cells of organisms. Several methods have been developed to insert information into a DNA sequence for the purpose of data storage, watermarking, or communication of secret messages. The ability to detect, extract, and decode messages from DNA is important for forensic data collection and for data security. We have developed a software toolkit that is able to detect the presence of a hidden message within a DNA sequence, extract that message, and then decode it. The toolkit is able to detect, extract, and decode …

Feasibility Testing Of Chill Filtration Of Brown Spirits To Increase Product Stability., Juan Cristobal Merizalde Carrillo

Electronic Theses and Dissertations

This thesis summarizes a feasibility study focused on filtering American whiskey, matured in new toasted and charred casks, at 25 ºF in order to remove haze which forms when product is diluted from cask strength (62% ABV) to bottling strength (40 – 50% ABV). Chill filtration is a process already implemented in the brown spirits industry in order to guarantee the stability of products at different ethyl alcohol concentrations. The filtration trials and cellulose-pad performance were evaluated in terms of economics, turbidity reduction, test time, throughput, color reduction, and shelf life stability. Those trials with satisfactory overall color and stability …

Artifical Neural Network Models For The Analysis Of Permeable Pavement Performance., Ata Radfar

Electronic Theses and Dissertations

This dissertation is a numerical modeling study based on the findings of the two installed Permeable Interlocking Concrete Pavements (PICPs) in Louisville, KY and twenty one laboratory models. A new model derived to more accurately predict the captured surface runoff volume by the PICPs using Artificial Neural Networks (ANNs). The proposed model relates rainfall parameters and site characteristics to the runoff volume captured by the permeable pavements. The database used for developing the prediction models is obtained from the collected data of the monitored permeable pavements. The performance of the ANN-based models are analyzed and the results demonstrate that the …

Bi-Stable Buckled Energy Harvesters Actuated Via Torque Arms., Daniel Allen Porter

Electronic Theses and Dissertations

Vibrational energy harvesters (VEH) are one way to generate electricity. Though the energy quantities are not enough to run desktop computers, they can power remote devices such as temperature, pressure, and accelerometer sensors or power biological implants. New versions of the Bluetooth protocol can even be used with VEH technology to send wireless data. An important aspect of VEH devices is the power output, operating frequency, and bandwidth. This dissertation investigates a novel method of actuating the primary buckled energy harvesting structure using torque arms as a force amplification mechanism. Buckled structures can exhibit snap-through and has the potential to …

Nanoscale Electrode Architectures For Electrochemical Energy Conversion And Storage., Venkat Kalyan Vendra

Electronic Theses and Dissertations

Nanoscale electrode architectures are at the heart of photoelectrochemical devices converting sunlight into electricity and electrochemical devices that store energy. Advanced nanomaterials encompassing 1-D architectures such as single crystalline metal oxide nanowires, 2-D architectures such graphene nanosheets and nanoparticle-nanowire hybrids have garnered significant interest as promising materials for fabricating thicker electrodes due their unique electronic, phase transformation and strain relaxation properties. However, electrode architectures incorporating these advanced nanomaterials will have a transformational impact on large scale electrode manufacturing only if the challenges associated with the electrode durability are addressed. At a fundamental level, the reactions happening at the electrode-electrolyte interface …

Development Of A Surrogate Bruising Detection System To Describe Potential Bruising Patterns Associated With Common Childhood Falls., Raymond Dsouza

Electronic Theses and Dissertations

Child abuse is a leading cause of fatality in children aged 0-4 years. An estimated 1,700 children die annually as a result of child abuse of which threequarters (75.7%) of the children were younger than 4 years old1. Infants (younger than 1 year) had the highest rate of fatalities among the group. Many of the serious injuries and fatalities could have potentially been prevented if clinicians and child protective services were able to better distinguish between injuries associated with abuse versus those caused by accidents. Missed cases of child abuse have been shown to be as high as 71% of …

Community Engagement, Environmental Education, And Public Outreach In Sustainable Engineering : A Collaborative Demonstration Project For Water Treatment Using Natural Processes And Sustainable Materials., Venkata Durga Prasad Gullapalli

Electronic Theses and Dissertations

Community engagement through environmental education for the public is an important component in the link between individual citizens, their community, and local government agencies responsible for maintaining urban recreation and park areas. Streams and waterways passing through urban areas are often misunderstood by the public in terms of whether the waterway is natural, constructed, or a combination of both. Additionally, aspects of water quality or water pollution are often obscure to the community and there are limited means to provide direct information to the public. In any case, the public are often drawn to interact with urban streams through recreation …

Experimental And Analytical Study Of An Open Cathode Polymer Electrolyte Membrane Fuel Cell., Alex Martin Bates

Electronic Theses and Dissertations

In this thesis four different fuel cell designs were simulated with consideration for electrochemical effects, reactant species transport, and heat transfer. Simulation results include the mass fraction of hydrogen, oxygen, and water, temperature gradient, pressure gradient, and velocity profile. One of the fuel cell designs was experimentally tested using two different membrane electrolyte assemblies; one high performance and the other high durability. The polarization curve resulting from simulation compares well with the polarization curve produced by experimental work. A 16 cell fuel cell stack was simulated with consideration for stack compression. The same fuel cell stack was tested experimentally for …

The Production, Properties And Applications Of The Zinc Imidazolate, Zif-8., John L. Tatarko Jr.

Electronic Theses and Dissertations

Venna, Carreon, and Jasinski produced and characterized the first samples of the zinc imidazolate framework ZIF-8 at the University of Louisville in 2010. In this dissertation the production, properties, and applications of this unique metal-organic framework are explored. Previously, only minute laboratory amounts (1/4 gram), of ZIF-8 were produced via time-consuming and expensive processes. Production quantities have been synthesized via both a continuous and a batch process using a spray drying operation to effect separation of the solid product (ZIF-8) from the mother liquor. Approximately 85% of the mother liquor (methanol), can be recovered from the spray dryer resulting in …

Simulation-Based Optimization Of Mitigation Strategies For Pandemic Influenza., Arsalan Paleshi

Electronic Theses and Dissertations

Millions of people have been infected and died as results of influenza pandemics in human history. In order to prepare for these disasters, it is important to know how the disease spreads. Further, intervention strategies should be implemented during the pandemics to mitigate their ill effects. Knowledge of how these interventions will affect the pandemic course is paramount for decision makers. This study develops a simulation-based optimization model which aims at finding a combination of strategies that result in the best value for an objective function of defined metrics under a set of constraints. Also, a procedure is presented to …

Speech Data Analysis For Semantic Indexing Of Video Of Simulated Medical Crises., Shuangshuang Jiang

Electronic Theses and Dissertations

The Simulation for Pediatric Assessment, Resuscitation, and Communication (SPARC) group within the Department of Pediatrics at the University of Louisville, was established to enhance the care of children by using simulation based educational methodologies to improve patient safety and strengthen clinician-patient interactions. After each simulation session, the physician must manually review and annotate the recordings and then debrief the trainees. The physician responsible for the simulation has recorded 100s of videos, and is seeking solutions that can automate the process. This dissertation introduces our developed system for efficient segmentation and semantic indexing of videos of medical simulations using machine learning …

Computational Methods To Predict And Enhance Decision-Making With Biomedical Data., Behnaz Abdollahi

Electronic Theses and Dissertations

The proposed research applies machine learning techniques to healthcare applications. The core ideas were using intelligent techniques to find automatic methods to analyze healthcare applications. Different classification and feature extraction techniques on various clinical datasets are applied. The datasets include: brain MR images, breathing curves from vessels around tumor cells during in time, breathing curves extracted from patients with successful or rejected lung transplants, and lung cancer patients diagnosed in US from in 2004-2009 extracted from SEER database. The novel idea on brain MR images segmentation is to develop a multi-scale technique to segment blood vessel tissues from similar tissues …

3d-Reconstruction Of Human Jaw From A Single Image : Integration Between Statistical Shape From Shading And Shape From Shading., Mohamad Ghanoum 1990-

Electronic Theses and Dissertations

Object modeling is a fundamental problem in engineering, involving talents from computer-aided design, computational geometry, computer vision and advanced manufacturing. The process of object modeling takes three stages: sensing, representation, and analysis. Various sensors may be used to capture information about objects; optical cam- eras and laser scanners are common with rigid objects, while X-ray, CT and MRI are common with biological organs. These sensors may provide a direct or indirect inference about the object, requiring a geometric representation in the computer that is suitable for subsequent usage. Geometric representations that are compact, i.e., capture the main features of the …

Challenges Of Implementing Automatic Dependent Surveillance Broadcast In The Nextgen Air Traffic Management System, Carl J. Giannatto Jr.

Electronic Theses and Dissertations

The Federal Aviation Administration is in the process of replacing the current Air Traffic Management (ATM) system with a new system known as NextGen. Automatic Dependent Surveillance-Broadcast (ADS-B) is the aircraft surveillance protocol currently being introduced as a part of the NextGen system deployment. The evolution of ADS-B spans more than two decades, with development focused primarily on increasing the capacity of the Air Traffic Control (ATC) system and reducing operational costs. Security of the ADS-B communications network has not been a high priority, and the inherent lack of security measures in the ADS-B protocol has come under increasing scrutiny …

Data Driven Comprehensive Assessment Of The Performance Of Stormwater Best Management Practices., Shanshan Li

Electronic Theses and Dissertations

In order to evaluate the performance of the stormwater best management practices (BMPs) installed on the Belknap campus at the University of Louisville, a comprehensive assessment on the stormwater BMPs’ the flow volume reduction, peak flow attenuation, and overflow area abatement was made. We used a two-pronged analysis based on 1) predictive modeling using data mining approach; 2) model-based hydraulic simulation. The novelty of study is that it not only assessed the stormwater BMPs’ performances on flow volume reduction, but also assessed their performance on peak flow attenuation which is neglected in previous studies and assessment practices. Flow volume reduction …

Face Modeling For Face Recognition In The Wild., Eslam Abdelfattah Mostafa

Electronic Theses and Dissertations

Face understanding is considered one of the most important topics in computer vision field since the face is a rich source of information in social interaction. Not only does the face provide information about the identity of people, but also of their membership in broad demographic categories (including sex, race, and age), and about their current emotional state. Facial landmarks extraction is the corner stone in the success of different facial analyses and understanding applications. In this dissertation, a novel facial modeling is designed for facial landmarks detection in unconstrained real life environment from different image modalities including infra-red and …

An Island-Based Approach For Rna-Seq Differential Expression Analysis., Abdallah Eteleeb

Electronic Theses and Dissertations

High-throughput mRNA sequencing (also known as RNA-Seq) promises to be the technique of choice for studying transcriptome profiles, offering several advantages over old techniques such as microarrays. This technique provides the ability to develop precise methodologies for a variety of RNA-Seq applications including gene expression quantification, novel transcript and exon discovery, differential expression (DE) and splice variant detection. The detection of significantly changing features (e.g. genes, transcript isoforms, exons) in expression across biological samples is a primary application of RNA-Seq. Uncovering which features are significantly differentially expressed between samples can provide insight into their functions. One major limitation with the …

Reducing Radio Frequency Susceptibilities In Commercial-Off-The-Shelf Camera Equipment For Use In Electromagnetic Compatibility Testing, Kevin Mainini

Electronic Theses and Dissertations

The Technical Testing and Analysis Center (TTAC) Group at Oak Ridge National Laboratory performs electromagnetic compatibility testing on various radiation detection units. These tests require remote viewing of the equipment’s display to monitor its compliance with national and international standards. The Commercial-Off-the-Shelf (COTS) camera equipment that is used to monitor the displays exhibits radio frequency susceptibilities causing issues when determining the actual susceptibilities of the device under test. In order to mitigate this issue, a COTS camera was placed in two common test positions and cycled through three angled orientations with various radio frequency shielding methods applied. The development of …

Development Of A Neuromusculoskeletal Computer Model In A Chondrodystrophic Dog., Gregory Russo States

Electronic Theses and Dissertations

Intervertebral disc disease (IVDD) is a naturally occurring disease in dogs that produces a spontaneous injury to the spinal cord. IVDD is characterized by mineralization of the intervertebral disc nucleus pulposus, which reduces its load bearing capacity and results in high rates of intervertebral disc herniation (IVDH). IVDH is disproportionately present in Dachshunds compared to other breeds, affecting an estimated 1 in 5 Dachshunds during their lifetime (Levine, J. M. et al., 2011). Assessment of injury severity and recovery in animal models is generally performed using a point scale, where subjects are graded according to metrics such as pain perception, …

Dosi In Novel Geometry Dishes, Jonathan Lawrence Lambert Jones

Electronic Theses and Dissertations

Effects of hemodynamic forces on cellular response are well studied. Wall shear stress is regularly accepted as the primary hemodynamic force affecting cellular response. Hemodynamic forces studies utilize Petri dishes on orbital shakers to grow cells for the experiments since this is an easily scalable system. However, characterizing the hemodynamics is difficult since the oscillatory swirling motion creates multidirectional and variable magnitude shear throughout the dish. Thus, a novel geometry dish that could create uniaxial shear with less variation in magnitude would be advantageous for studying shear stress effects on cellular response. The purpose of this thesis was to explore …

Fail-Safe Test Generation Of Safety Critical Systems, Salwa Elakeili

Electronic Theses and Dissertations

This dissertation introduces a technique for testing proper failure mitigation in safety critical systems. Unlike other approaches which integrate behavioral and failure models, and then generate tests from the integrated model, we build safety mitigation tests from an existing behavioral test suite, using an explicit mitigation model for which we generate mitigation paths which are then woven at selected failure points into the original test suite to create failure-mitigation tests (safety mitigation test).

Synchrophasor Sensing And Processing Based Smart Grid Security Assessment For Renewable Energy Integration, Huaiguang Jiang

Electronic Theses and Dissertations

With the evolution of energy and power systems, the emerging Smart Grid (SG) is mainly featured by distributed renewable energy generations, demand-response control and huge amount of heterogeneous data sources. Widely distributed synchrophasor sensors, such as phasor measurement units (PMUs) and fault disturbance recorders (FDRs), can record multi-modal signals, for power system situational awareness and renewable energy integration.

An effective and economical approach is proposed for wide-area security assessment. This approach is based on wavelet analysis for detecting and locating the short-term and long-term faults in SG, using voltage signals collected by distributed synchrophasor sensors.

A data-driven approach for fault …

Microgrid Optimal Scheduling Considering Impact Of High Penetration Wind Generation, Abdulaziz Furreh Alanazi

Electronic Theses and Dissertations

The objective of this thesis is to study the impact of high penetration wind energy in economic and reliable operation of microgrids. Wind power is variable, i.e., constantly changing, and nondispatchable, i.e., cannot be controlled by the microgrid controller. Thus an accurate forecasting of wind power is an essential task in order to study its impacts in microgrid operation. Two commonly used forecasting methods including Autoregressive Integrated Moving Average (ARIMA) and Artificial Neural Network (ANN) have been used in this thesis to improve the wind power forecasting. The forecasting error is calculated using a Mean Absolute Percentage Error (MAPE) and …

Assessment Of Normal Knee Kinematics Using High-Speed Stereo-Radiography System, Vasiliki Kefala

Electronic Theses and Dissertations

The measurement of dynamic joint kinematics in vivo is important in order to understand the effects of joint injuries and diseases as well as for evaluating the treatment effectiveness. Quantification of knee motion is essential for assessment of joint function for diagnosis of pathology, such as tracking and progression of osteoarthritis and evaluation of outcome following conservative or surgical treatment. Total knee arthroplasty (TKA) is an invasive treatment for arthritic pain and functional disability and it is used for deformed joint replacement with implants in order to restore joint alignment. It is important to describe knee kinematics in healthy individuals …

Broadband Coherent Perfect Absorption In One-Dimensional Optical Systems, Massimo Maximilian Villinger

Electronic Theses and Dissertations

Absorption plays a critical role in a variety of optical applications – sometimes it is desirable to minimize it as in optical fibers and waveguides, or to enhance it as in solar cells and photodetectors. We describe here a new optical scheme that controllably produces high optical absorption over a broad wavelength range (hundreds of nm) in systems that have low intrinsic absorption over the same range. This effect, 'coherent perfect absorption' or CPA, arises from a subtle interplay between interference and absorption of two beams incident on a weakly absorbing medium. In the first part of this study, we …

Nanoarchitectured Energy Storage Devices, Zenan Yu

Electronic Theses and Dissertations

Supercapacitors, the devices that connect the gap between batteries and conventional capacitors, have recently attracted significant attention due to their high specific capacitance, substantially enhanced power and energy densities, and extraordinary cycle life. In order to realize even better performance with supercapacitors, rejuvenated effort towards developing nanostructured electrodes is necessary. In this dissertation, several strategic directions of nanoarchitecturing the electrodes to enhance the performance of supercapacitors are investigated. An introduction and background of supercapacitors, which includes motivation, classification and working principles, recent nanostructured electrode materials studies, and devices fabrication, are initially presented. A facile method, called Spin-on Nanoprinting (SNAP), to …