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Full-Text Articles in Engineering
Microengineering The Neural Tube, Christopher Demers
Microengineering The Neural Tube, Christopher Demers
Electronic Theses and Dissertations
Early embryonic development is a complex and highly regulated orchestra of instructive cues that collectively guide naïve stem cells towards progressively more specialized fates. In the neural tube, the precursor structure to the brain and spinal cord, these signals emanate from ‘organizing centers’ surrounding the neural tube. These organizing centers send out soluble cues or morphogens that diffuse tens to hundreds of microns to recipient cells residing in the neural tube. Re-creating this dynamic landscape of cues in vitro is impossible using standard cell culture tools and techniques. However, microfluidics is perfectly suited to fill this gap, allowing precise control …
Assessment Of Electrode Configurations Of Electrical Impedance Myography For The Evaluation Of Neuromuscular Diseases, Khondokar Mohammad Fazle Rabbi
Assessment Of Electrode Configurations Of Electrical Impedance Myography For The Evaluation Of Neuromuscular Diseases, Khondokar Mohammad Fazle Rabbi
Electronic Theses and Dissertations
Electrical impedance myography (EIM) is a painless, noninvasive approach to measure the neuromuscular disease status. EIM parameters- resistance (R), reactance (X) and phase (θ) depend significantly on subcutaneous fat thickness, muscle size and inter electrode distance. The objective of this research is to find an electrode configuration which can minimize the effects on EIM parameters due to subcutaneous fat thickness variation. In this study, a model of human upper arm was developed using finite element method (FEM), which has already been established as an appropriate approach for the analysis of non-symmetrical shape for assessing alternations of muscle in disease-induced changes …