Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Theses/Dissertations

Electronic Thesis and Dissertation Repository

Physical Sciences and Mathematics

2013

Atherosclerosis

Articles 1 - 1 of 1

Full-Text Articles in Engineering

Piv-Based Investigation Of Hemodynamic Factors In Diseased Carotid Artery Bifurcations With Varying Plaque Geometries, Sarah Kefayati Aug 2013

Piv-Based Investigation Of Hemodynamic Factors In Diseased Carotid Artery Bifurcations With Varying Plaque Geometries, Sarah Kefayati

Electronic Thesis and Dissertation Repository

Ischemic stroke is often a consequence of complications due to clot formation (i.e. thrombosis) at the site of an atherosclerotic plaque developed in the internal carotid artery. Hemodynamic factors, such as shear-stress forces and flow disturbances, can facilitate the key mechanisms of thrombosis. Atherosclerotic plaques can differ in the severity of stenosis (narrowing), in eccentricity (symmetry), as well as inclusion of ulceration (wall roughness). Therefore, in terms of clinical significance, it is important to investigate how the local hemodynamics of the carotid artery is mediated by the geometry of plaque. Knowledge of thrombosis-associated hemodynamics may provide a basis to ...