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Theses/Dissertations

Electronic Thesis and Dissertation Repository

Mechanical Engineering

Porous media

2013

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Numerical Modelling Of Species Exchange In A 3d Porous Medium: Modelling Exchange Within The Human Lung, Chelsea E. Johnson Apr 2013

Numerical Modelling Of Species Exchange In A 3d Porous Medium: Modelling Exchange Within The Human Lung, Chelsea E. Johnson

Electronic Thesis and Dissertation Repository

The volume-averaged oxygen transport equation is closed using a volume-averaged form of Fick’s law of diffusion between the air and tissue to simulate species exchange within the lungs’ alveoli using a computational fluid dynamics (CFD) 3D conjugate domain model. Pore level simulations of a terminal alveolated duct are used to determine that the transport of inhaled oxygen from the cluster inlet to the alveolar walls is diffusion dominated. The resistance to oxygen diffusion into the tissue is found to be a function of the tidal volume and tissue transport properties, with a maximum respiration frequency at which the full ...